SCHEMBL4774885

SCHEMBL4774885

CCCCCCCCCCCCCC[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.40
THRB P10828 1/20 0.40
LMNA P02545 3/20 0.32
DNM1 Q05193 6/20 0.32
ALDH1A1 P00352 3/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
HSD17B10 Q99714 1/20 0.32
SLC22A1 O15245 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14270566 1.00 TSHR (0.40) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL5711705 1.00 TSHR (0.40) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL1915388 1.00 TSHR (0.40) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL11926993 1.00 TSHR (0.40) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL1959828 1.00 TSHR (0.40) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL727806 1.00 TSHR (0.40) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL727830 1.00 TSHR (0.40) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL20477180 1.00 TSHR (0.40) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL21114738 1.00 TSHR (0.40) TSHRTHRBLMNADNM1ALDH1A1
SCHEMBL29766725 1.00 TSHR (0.40) TSHRTHRBLMNADNM1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724153-A1 SUNSCREEN COMPOSITIONS AND METHODS OF USE Mary Kay, Inc. (US) 2026-04-15 EP claimed
US-20250262154-A1 A NON-AQUEOUS SPRAY COMPOSITION AMATERASU LIFESCIENCES LLP. (IN) 2025-08-21 US claimed
EP-4566589-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTION AND ALLEVIATION OF EARLY SKIN REACTIONS CAUSED BY IRRADIATION IN PATIENTS TREATED FOR CANCER Verco Spolka Akcyjna (PL) 2025-06-11 EP claimed
US-20240407996-A1 SUNSCREEN COMPOSITIONS AND METHODS OF USE MARY KAY INC. (US) 2024-12-12 US claimed
WO-2024253961-A1 SUNSCREEN COMPOSITIONS AND METHODS OF USE MARY KAY INC. (US) 2024-12-12 WO claimed
US-20260137615-A1 Anhydrous Sunscreen Compositions With enhanced Ultraviolet Protection ELC MAN LLC (US) 2026-05-21 US disclosed
EP-4724153-A1 SUNSCREEN COMPOSITIONS AND METHODS OF USE Mary Kay, Inc. (US) 2026-04-15 EP disclosed
US-12502339-B2 Foam compositions THE PROCTER & GAMBLE COMPANY (US) 2025-12-23 US disclosed
EP-3719056-B1 ORGANIC GROUP-MODIFIED ORGANOSILICON RESIN, PRODUCTION METHOD THEREOF, AND COSMETIC SHINETSU CHEMICAL CO (JP) 2025-08-27 EP disclosed
US-20250262154-A1 A NON-AQUEOUS SPRAY COMPOSITION AMATERASU LIFESCIENCES LLP. (IN) 2025-08-21 US disclosed
EP-4566589-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTION AND ALLEVIATION OF EARLY SKIN REACTIONS CAUSED BY IRRADIATION IN PATIENTS TREATED FOR CANCER Verco Spolka Akcyjna (PL) 2025-06-11 EP disclosed
EP-3768762-B1 SILICONE POLYMER MOMENTIVE PERFORMANCE MAT INC (US) 2025-02-19 EP disclosed
US-10717887-B2 Oil-based inkjet ink RISO KAGAKU CORPORATION (JP) 2020-07-21 US disclosed
US-20180244939-A1 OIL-BASED INKJET INK RISO KAGAKU CORPORATION (JP) 2018-08-30 US disclosed
EP-3366737-A1 OIL-BASED INKJET INK Riso Kagaku Corporation (JP) 2018-08-29 EP disclosed
US-9932446-B2 Method of manufacturing a purified product of alkyl-modified polydimethylsiloxane, a cosmetic raw material, and cosmetics DOW CORNING TORAY CO., LTD. (JP) 2018-04-03 US disclosed
EP-1894994-B1 Two or more phase face cleansing agent with improved reversible mixing and demixing solution HENKEL AG & CO KGAA (DE) 2013-10-16 EP disclosed
US-20120202893-A1 Method Of Manufacturing A Purified Product Of Alkyl-Modified Polydimethylsiloxane, A Cosmetic Raw Material, And Cosmetics DOW TORAY CO., LTD. (JP) 2012-08-09 US disclosed
EP-1902704-A1 Cosmetic compositions containing a combination of silicon-elastomers Henkel KGaA (DE) 2008-03-26 EP disclosed
EP-1894994-A1 Two or more phase face cleansing agent with improved reversible mixing and demixing solution Henkel KGaA (DE) 2008-03-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12502339-B2 Foam compositions DSG1, DAGLA, DEK TSHR 3631/4885THRB 4039/4885LMNA 3144/4885
US-20260137615-A1 Anhydrous Sunscreen Compositions With enhanced Ultraviolet Protection OGFOD1, ERCC2, OGG1 TSHR 4445/4885THRB 4262/4885LMNA 3563/4885
US-20120202893-A1 Method Of Manufacturing A Purified Product Of Alkyl-Modified Polydimethylsiloxane, A Cosmetic Raw Material, And Cosmetics OR10J3, CUTA, DEGS1 TSHR 3657/4885THRB 3548/4885LMNA 2103/4885
US-20240407996-A1 SUNSCREEN COMPOSITIONS AND METHODS OF USE OGG1, RAD23B, RAD50 TSHR 4116/4885THRB 3633/4885LMNA 1823/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.