Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4774885 | 1.00 | TSHR (0.40) | TSHRTHRBLMNADNM1ALDH1A1 | |
| SCHEMBL14270566 | 1.00 | TSHR (0.40) | TSHRTHRBLMNADNM1ALDH1A1 | |
| SCHEMBL5711705 | 1.00 | TSHR (0.40) | TSHRTHRBLMNADNM1ALDH1A1 | |
| SCHEMBL1915388 | 1.00 | TSHR (0.40) | TSHRTHRBLMNADNM1ALDH1A1 | |
| SCHEMBL11926993 | 1.00 | TSHR (0.40) | TSHRTHRBLMNADNM1ALDH1A1 | |
| SCHEMBL1959828 | 1.00 | TSHR (0.40) | TSHRTHRBLMNADNM1ALDH1A1 | |
| SCHEMBL727806 | 1.00 | TSHR (0.40) | TSHRTHRBLMNADNM1ALDH1A1 | |
| SCHEMBL20477180 | 1.00 | TSHR (0.40) | TSHRTHRBLMNADNM1ALDH1A1 | |
| SCHEMBL21114738 | 1.00 | TSHR (0.40) | TSHRTHRBLMNADNM1ALDH1A1 | |
| SCHEMBL29766725 | 1.00 | TSHR (0.40) | TSHRTHRBLMNADNM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107034002-B | Environment-friendly aqueous demolding release composition | 中山市润发纺织材料有限公司 | 2020-01-10 | — | — | CN | claimed |
| JP-2011527341-A | — | — | 2011-10-27 | — | — | JP | claimed |
| US-8017687-B2 | Swollen silicone composition and process of producing same | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2011-09-13 | — | — | US | claimed |
| EP-2296667-A2 | SILICONE COMPOSITION | Momentive Performance Materials Inc. (US) | 2011-03-23 | — | — | EP | claimed |
| EP-2228053-A1 | Swollen silicone composition and process of producing same | Momentive Performance Materials Inc. (US) | 2010-09-15 | — | — | EP | claimed |
| JP-2010515566-A | — | — | 2010-05-13 | — | — | JP | claimed |
| WO-2010005538-A2 | SILICONE COMPOSITION | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2010-01-14 | — | — | WO | claimed |
| US-20100003201-A1 | Silicone composition | MOMENTIVE PERFORMANCE MATERIALS, INC. | 2010-01-07 | — | — | US | claimed |
| EP-2108028-A2 | METHOD OF APPLYING A COMPOSITION | Momentive Performance Materials Inc. (US) | 2009-10-14 | — | — | EP | claimed |
| JP-2009516024-A | — | — | 2009-04-16 | — | — | JP | claimed |
| US-6258365-B1 | SILICONE-HYDROCARBON HYBRID FLUID COMPROSING TRISILOXANE OR TRIS(SILOXY)SILANE COMPOUND; COSMETICS FOR DRY SKIN TREATMENT | ARCHIMICA (FLORIDA), INC. | 2001-07-10 | — | — | US | claimed |
| US-6036967-A | Mixtures of trimethylsilylated silicas and alkylsiloxanes | ARCHIMICA (FLORIDA), INC. (US) | 2000-03-14 | — | — | US | claimed |
| US-5961731-A | Method for removing deleterious deposits from a surface | COOPER-TROTTER EUNICE (US) | 1999-10-05 | — | — | US | claimed |
| US-5750098-A | Silicone compositions for skin care | DOW CORNING CORPORATION (US) | 1998-05-12 | — | — | US | claimed |
| EP-0610014-B1 | Silicone compositions for skin care | DOW CORNING (US) | 1996-07-24 | — | — | EP | claimed |
| US-5468417-A | Silicone containing VOC complaint paint remover | DOW CORNING CORPORATION (US) | 1995-11-21 | — | — | US | claimed |
| EP-0662313-A1 | Silicone containing low VOC paint remover | DOW CORNING CORPORATION (US) | 1995-07-12 | — | — | EP | claimed |
| EP-0657157-A1 | Styling aid containing a volatile alkylmethylsilicone | DOW CORNING CORPORATION (US) | 1995-06-14 | — | — | EP | claimed |
| US-5403402-A | Applying a fluid containing acetone, volatile silicon fluid and water, rubbing; nail polish remover and can be used to remove acrylic enamel from painted steel surfaces | DOW CORNING CORPORATION (US) | 1995-04-04 | — | — | US | claimed |
| EP-0610014-A1 | Silicone compositions for skin care | DOW CORNING CORPORATION (US) | 1994-08-10 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100003201-A1 | Silicone composition | CUTA, SMURF1, MMS19 | TSHR 3819/4885THRB 3235/4885LMNA 339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.