Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7270332 | 0.85 | DHFR (0.48) | SMN1; SMN2ADORA1ALDH1A1 | |
| SCHEMBL7279899 | 0.81 | ADORA1 (0.44) | GAAP2RX7ADORA1ALDH1A1 | |
| SCHEMBL7436318 | 0.75 | ADORA1 (0.46) | LMNAGAAHSD17B10ADORA1ALDH1A1 | |
| SCHEMBL8705434 | 0.75 | ADORA1 (0.39) | GAAADORA1ALDH1A1 | |
| SCHEMBL10858163 | 0.75 | ALDH1A1 (0.43) | LMNASMN1; SMN2GAAHSD17B10ADORA1 | |
| SCHEMBL8706002 | 0.75 | ADORA1 (0.36) | LMNAGAAHSD17B10ADORA1ALDH1A1 | |
| SCHEMBL8710355 | 0.73 | TDP1 (0.35) | LMNAGAAHSD17B10ADORA1ALDH1A1 | |
| SCHEMBL8397308 | 0.73 | ADORA2A (0.42) | GAAHSD17B10ADORA1ALDH1A1 | |
| SCHEMBL7278269 | 0.72 | KCNQ3 (0.46) | GAAHSD17B10ALDH1A1 | |
| SCHEMBL7274817 | 0.71 | NPSR1 (0.38) | LMNASMN1; SMN2GAAHSD17B10CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415456-B1 | Xanthine compounds | KYOWA HAKKO KOGYO KK (JP) | 1996-06-26 | — | — | EP | disclosed |
| US-5525607-A | DIURETICS, BRONCHODILATORS, RENAL PROTECTING AGENTS | KYOWA HAKKO KOGYO CO., LTD (JP) | 1996-06-11 | — | — | US | disclosed |
| US-5290782-A | Bronchodilator agents, diuretics for renal protective agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-03-01 | — | — | US | disclosed |
| EP-0415456-A2 | Xanthine compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |