Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 9/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.35 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | EEF2K | O00418 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8706002 | 0.85 | ADORA1 (0.36) | TDP1ADORA1ADORA2AADORA3ADORA2B | |
| SCHEMBL8709010 | 0.83 | KDM4E (0.46) | GAAALDH1A1LMNA | |
| SCHEMBL7436318 | 0.82 | ADORA1 (0.46) | ADORA1ADORA2AADORA3ADORA2BSLC6A3 | |
| SCHEMBL8705434 | 0.81 | ADORA1 (0.39) | TDP1ADORA1ADORA2AADORA3ADORA2B | |
| SCHEMBL8707133 | 0.81 | PDE4A (0.38) | TDP1ADORA1ADORA2AADORA3ADORA2B | |
| SCHEMBL8397308 | 0.80 | ADORA2A (0.42) | ADORA1ADORA2AADORA3ADORA2BSLC6A3 | |
| SCHEMBL8208161 | 0.78 | ALDH1A1 (0.40) | TDP1ADORA1ADORA2AADORA3ADORA2B | |
| SCHEMBL7279799 | 0.77 | CNR2 (0.40) | TDP1ADORA1ADORA2AADORA3ADORA2B | |
| SCHEMBL7269080 | 0.76 | CNR2 (0.39) | ADORA1ADORA2AADORA3ADORA2BSLC6A3 | |
| SCHEMBL7278280 | 0.73 | LMNA (0.48) | ADORA1GAAALDH1A1HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0619316-B1 | Xanthine derivatives | KYOWA HAKKO KOGYO KK (JP) | 1998-08-12 | — | — | EP | disclosed |
| EP-0619316-A1 | Xanthine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-10-12 | — | — | EP | disclosed |