Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.55 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.55 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | MAP2K4 | P45985 | 3/20 | 0.38 |
| ▸ | TTK | P33981 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TYK2 | P29597 | 3/20 | 0.35 |
| ▸ | JAK3 | P52333 | 3/20 | 0.35 |
| ▸ | JAK1 | P23458 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | KIT | P10721 | 6/20 | 0.35 |
| ▸ | FLT3 | P36888 | 6/20 | 0.35 |
| ▸ | KDR | P35968 | 5/20 | 0.35 |
| ▸ | PLK4 | O00444 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 2/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2021782 | 0.76 | KDR (0.52) | CSNK1A1TYRO3DYRK1BMAP2K4TTK | |
| SCHEMBL8877409 | 0.72 | MAP2K4 (0.44) | CSNK1A1TYRO3PARP1MAP2K4TTK | |
| SCHEMBL1648452 | 0.72 | MAP2K4 (0.44) | MAP2K4TTKKDM4EJAK2KIT | |
| SCHEMBL6825869 | 0.71 | CSNK1A1 (1.00) | CSNK1A1TYRO3DYRK1BPARP1IDO1 | |
| SCHEMBL2723270 | 0.71 | MAP2K4 (0.49) | PARP1MAP2K4TTKKDM4EKIT | |
| SCHEMBL16252836 | 0.71 | MAP2K4 (0.43) | CSNK1A1TYRO3DYRK1BPARP1MAP2K4 | |
| SCHEMBL4244229 | 0.71 | PARP1 (0.56) | CSNK1A1TYRO3DYRK1BPARP1IDO1 | |
| SCHEMBL31169514 | 0.70 | TGFBR1 (0.38) | PARP1MAP2K4TTKDYRK1APIM1 | |
| Water SCHEMBL30473073 | 0.70 | CSNK1A1 (0.97) | CSNK1A1TYRO3DYRK1BPARP1IDO1 | |
| SCHEMBL4564865 | 0.70 | CSNK1A1 (0.73) | CSNK1A1TYRO3DYRK1BPARP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429984-B1 | Indole derivatives | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |