Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.46 |
| ▸ | PPIA | P62937 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5481199 | 0.95 | RAB9A (0.49) | RAB9ANPC1ITGA4ITGB7TDP1 | |
| SCHEMBL7294874 | 0.88 | IDO1 (0.43) | RAB9AIDO1MAPTALDH1A1HTT | |
| SCHEMBL10569475 | 0.88 | MAPT (0.45) | RAB9ANPC1IDO1MAPTALDH1A1 | |
| SCHEMBL3861174 | 0.88 | IDO1 (0.43) | RAB9AIDO1MAPTALDH1A1HTT | |
| SCHEMBL4438089 | 0.86 | GAA (0.53) | RAB9AMAPTALDH1A1HTTATM | |
| SCHEMBL7278760 | 0.86 | GAA (0.53) | RAB9AMAPTALDH1A1HTTATM | |
| SCHEMBL212215 | 0.85 | ALDH1A1 (0.51) | TDP1ALDH1A1NPSR1 | |
| SCHEMBL11004392 | 0.83 | ALOX5 (0.56) | RAB9ATDP1MAPTALDH1A1HTT | |
| SCHEMBL9368647 | 0.82 | RAB9A (0.46) | RAB9ANPC1IDO1ALDH1A1 | |
| SCHEMBL9050930 | 0.82 | MEN1 (0.43) | RAB9AIDO1MAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834486-A | ANTIPROLIFERATIVE, ANTIPROTOZOA AGENTS | NOVARTIS AG (CH) | 1998-11-10 | — | — | US | disclosed |
| US-5149802-A | Chemical intermediates for antibiotics | MERCIAN CORPORATION (JP) | 1992-09-22 | — | — | US | disclosed |
| US-5096899-A | Nonhydrolyzing oxapenicillins | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-17 | — | — | US | disclosed |
| EP-0163433-B1 | ANTIBACTERIAL SOLID COMPOSITION FOR ORAL ADMINISTATION | Takeda Chemical Industries, Ltd. (JP) | 1990-08-01 | — | — | EP | disclosed |
| EP-0008888-B1 | BETA-LACTAM ANTIBACTERIAL COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1983-09-21 | — | — | EP | disclosed |
| EP-0008888-A1 | Beta-lactam antibacterial compounds, their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1980-03-19 | — | — | EP | disclosed |