Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7336644 | 0.86 | ALDH1A1 (0.62) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL2341345 | 0.86 | ALDH1A1 (0.62) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL20854567 | 0.86 | ALDH1A1 (0.62) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL3138518 | 0.84 | ALDH1A1 (0.65) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL8009353 | 0.84 | ALDH1A1 (0.65) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL8009352 | 0.84 | ALDH1A1 (0.65) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL15985611 | 0.84 | DRD4 (0.43) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL9803136 | 0.83 | ALDH1A1 (0.59) | ALDH1A1TP53TSHRHIF1ACYP3A4 | |
| SCHEMBL15985607 | 0.83 | RAB9A (0.50) | ALDH1A1SMN1; SMN2MAPTTDP1LMNA | |
| SCHEMBL11592021 | 0.83 | ALDH1A1 (0.54) | ALDH1A1TP53TSHRHIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567264-A | ADRENERGIC BLOCKING AGENTS | SYNTEX (U.S.A.) INC. (US) | 1986-01-28 | — | — | US | disclosed |
| EP-0126449-A1 | Cardioselective aryloxy- and arylthio-hydroxypropyl piperazinyl acetanilides wich affect calcium entry | SYNTEX (U.S.A.) INC. (US) | 1984-11-28 | — | — | EP | disclosed |