Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7291960 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MAPTLMNAPOLBATM | |
| SCHEMBL7279730 | 0.79 | MEN1 (0.61) | ALDH1A1POLBATMNPC1SMN1; SMN2 | |
| SCHEMBL7282287 | 0.78 | NPC1 (0.58) | ALDH1A1MAPTLMNAPOLBATM | |
| SCHEMBL7282158 | 0.77 | ALDH1A1 (0.49) | ALDH1A1MAPTLMNAPOLBNPC1 | |
| SCHEMBL7278718 | 0.76 | ALDH1A1 (0.62) | ALDH1A1POLBNPC1SMN1; SMN2GFER | |
| SCHEMBL7292491 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MAPTLMNAATMNPC1 | |
| SCHEMBL7289666 | 0.75 | ALDH1A1 (0.54) | ALDH1A1LMNAATMNPC1MEN1 | |
| SCHEMBL10837614 | 0.74 | SMN1; SMN2 (0.46) | ALDH1A1MAPTLMNAATMNPC1 | |
| SCHEMBL7282542 | 0.74 | SIGMAR1 (0.58) | ALDH1A1MAPTNPC1SIGMAR1MEN1 | |
| SCHEMBL7278994 | 0.73 | SMN1; SMN2 (0.73) | ALDH1A1MAPTLMNAATMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567264-A | ADRENERGIC BLOCKING AGENTS | SYNTEX (U.S.A.) INC. (US) | 1986-01-28 | — | — | US | disclosed |
| EP-0126449-A1 | Cardioselective aryloxy- and arylthio-hydroxypropyl piperazinyl acetanilides wich affect calcium entry | SYNTEX (U.S.A.) INC. (US) | 1984-11-28 | — | — | EP | disclosed |