Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | REV1 | Q9UBZ9 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7544924 | 0.88 | SMN1; SMN2 (0.49) | MEN1KMT2ANPC1RAB9AHPGD | |
| SCHEMBL7429214 | 0.85 | MEN1 (0.61) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL7536797 | 0.83 | SMN1; SMN2 (0.49) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL7289666 | 0.83 | ALDH1A1 (0.54) | MEN1KMT2ANPC1ALDH1A1KDM4E | |
| SCHEMBL7278718 | 0.82 | ALDH1A1 (0.62) | MEN1KMT2APOLBNPC1SMN1; SMN2 | |
| SCHEMBL7536722 | 0.82 | SMN1; SMN2 (0.48) | MEN1KMT2ANPC1RAB9AHPGD | |
| SCHEMBL7538944 | 0.82 | SMN1; SMN2 (0.48) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL7292491 | 0.81 | ALDH1A1 (0.53) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7282287 | 0.81 | NPC1 (0.58) | MEN1KMT2APOLBNPC1RAB9A | |
| SCHEMBL7282067 | 0.81 | CHRM5 (0.51) | MEN1KMT2ANPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4567264-A | ADRENERGIC BLOCKING AGENTS | SYNTEX (U.S.A.) INC. (US) | 1986-01-28 | — | — | US | disclosed |
| US-4558129-A | Benzodioxanyl-hydroxyethylene-piperazinyl acetanilides which effect calcium entry and β-blockade | SYNTEX (U.S.A.) INC. (US) | 1985-12-10 | — | — | US | disclosed |
| EP-0126449-A1 | Cardioselective aryloxy- and arylthio-hydroxypropyl piperazinyl acetanilides wich affect calcium entry | SYNTEX (U.S.A.) INC. (US) | 1984-11-28 | — | — | EP | disclosed |