Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7271096 | 0.90 | CA1 (0.46) | ALDH1A1MEN1KMT2AADORA3ACHE | |
| SCHEMBL7280492 | 0.88 | CACNA1C (0.53) | ACHECACNA1FCACNA1DCACNA1SCACNA1C | |
| SCHEMBL7280765 | 0.85 | CACNA1D (0.54) | ALDH1A1MEN1KMT2AADORA3ACHE | |
| SCHEMBL7272872 | 0.84 | MTOR (0.58) | ALDH1A1ADORA3ACHEKDM4ECASP1 | |
| SCHEMBL7272356 | 0.83 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AADORA3ACHE | |
| SCHEMBL7273223 | 0.80 | CACNA1F (0.55) | ALDH1A1MEN1KMT2AADORA3ACHE | |
| SCHEMBL7282275 | 0.78 | CA1 (0.49) | ALDH1A1MEN1KMT2AADORA3ACHE | |
| SCHEMBL7271466 | 0.78 | CACNA1C (0.54) | ALDH1A1MEN1KMT2AADORA3ACHE | |
| SCHEMBL3027183 | 0.77 | ADORA3 (0.59) | ALDH1A1MEN1KMT2AADORA3KDM4E | |
| SCHEMBL7271341 | 0.77 | CACNA1F (0.66) | MEN1KMT2AADORA3ACHETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114273-B1 | NEW PHARMACOLOGICALLY ACTIVE PYRAZOLOPYRIDINES | GRUPPO LEPETIT S.p.A. (IT) | 1991-11-06 | — | — | EP | disclosed |
| US-4954508-A | HYPOTENSIVE | GRUPPO LEPETIT S.P.A. (IT) | 1990-09-04 | — | — | US | disclosed |
| EP-0114273-A1 | New pharmacologically active pyrazolopyridines | GRUPPO LEPETIT S.p.A. (IT) | 1984-08-01 | — | — | EP | disclosed |