Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 3/20 | 0.53 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.53 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.53 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7280324 | 0.88 | ALDH1A1 (0.48) | CACNA1CCACNA1FCACNA1DCACNA1SACHE | |
| SCHEMBL7271096 | 0.88 | CA1 (0.46) | CACNA1CCACNA1FCACNA1DCACNA1SACHE | |
| SCHEMBL7280765 | 0.83 | CACNA1D (0.54) | CACNA1CCACNA1FCACNA1DCACNA1SACHE | |
| SCHEMBL7273223 | 0.83 | CACNA1F (0.55) | CACNA1CCACNA1FCACNA1DCACNA1SACHE | |
| SCHEMBL7272356 | 0.80 | ALDH1A1 (0.42) | ACHE | |
| SCHEMBL7272872 | 0.80 | MTOR (0.58) | CACNA1CCACNA1FCACNA1DCACNA1SACHE | |
| SCHEMBL7279048 | 0.79 | CYP1A2 (0.57) | CACNA1CCACNA1FCACNA1DCACNA1SACHE | |
| SCHEMBL7431826 | 0.79 | CACNA1C (0.71) | CACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL9765757 | 0.76 | CACNA1C (0.69) | CACNA1CCACNA1FCACNA1DCACNA1S | |
| SCHEMBL7282275 | 0.76 | CA1 (0.49) | CACNA1CCACNA1FCACNA1DCACNA1SACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114273-B1 | NEW PHARMACOLOGICALLY ACTIVE PYRAZOLOPYRIDINES | GRUPPO LEPETIT S.p.A. (IT) | 1991-11-06 | — | — | EP | disclosed |
| US-4954508-A | HYPOTENSIVE | GRUPPO LEPETIT S.P.A. (IT) | 1990-09-04 | — | — | US | disclosed |
| EP-0114273-A1 | New pharmacologically active pyrazolopyridines | GRUPPO LEPETIT S.p.A. (IT) | 1984-08-01 | — | — | EP | disclosed |