Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 5/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | UBE2N | P61088 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7283709 | 0.86 | ITGB3 (0.52) | KMT2AALDH1A1POLBCTDSP1LMNA | |
| SCHEMBL8770197 | 0.83 | NPC1 (0.51) | KMT2AALDH1A1POLBLMNAL3MBTL1 | |
| SCHEMBL7293325 | 0.83 | POLB (0.44) | KMT2AALDH1A1POLBLMNAL3MBTL1 | |
| SCHEMBL8770183 | 0.83 | NPC1 (0.51) | KMT2AALDH1A1POLBLMNAL3MBTL1 | |
| SCHEMBL7283738 | 0.83 | POLB (0.44) | KMT2AALDH1A1POLBLMNAL3MBTL1 | |
| SCHEMBL7292912 | 0.80 | ALDH1A1 (0.52) | KMT2AALDH1A1POLBCTDSP1LMNA | |
| SCHEMBL8770195 | 0.80 | POLB (0.70) | KMT2AALDH1A1POLBL3MBTL1MAPT | |
| SCHEMBL8359480 | 0.79 | ALDH1A1 (0.49) | KMT2AALDH1A1POLBCTDSP1LMNA | |
| SCHEMBL2116437 | 0.78 | PTGS2 (0.66) | KMT2AALDH1A1POLBLMNAL3MBTL1 | |
| SCHEMBL9273376 | 0.76 | MEN1 (0.52) | KMT2AALDH1A1POLBL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981531-A | FOR INHIBITING PLATELET AGGREGATION | ZENECA LIMITED (GB) | 1999-11-09 | — | — | US | disclosed |
| US-5760057-A | ANTICOAGULANTS | ZENECA LIMITED (GB) | 1998-06-02 | — | — | US | disclosed |
| EP-0632016-B1 | 1,2-Diacylated hydrazine derivatives and their use as cell adhesion inhibitors | ZENECA LTD (GB) | 1997-04-09 | — | — | EP | disclosed |
| US-5612373-A | ANTICOAGULANTS | ZENECA LIMITED (GB) | 1997-03-18 | — | — | US | disclosed |
| WO-1995000472-A1 | 1,2 DIACYLATED HYDRAZINE DERIVATIVES AND THEIR USE AS ALL ADHESION INHIBITORS | ZENECA LIMITED (GB) | 1995-01-05 | — | — | WO | disclosed |
| EP-0632016-A1 | 1,2-Diacylated hydrazine derivatives and their use as cell adhesion inhibitors | ZENECA LIMITED (GB) | 1995-01-04 | — | — | EP | disclosed |