Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | PARP10 | Q53GL7 | 10/20 | 0.62 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.58 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | PARP1 | P09874 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.54 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.52 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.52 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2116437 | 0.87 | PTGS2 (0.66) | POLBMAPTKMT2AGAAL3MBTL1 | |
| SCHEMBL10299626 | 0.85 | PTGS2 (0.57) | POLBMAPTKMT2AGAAL3MBTL1 | |
| SCHEMBL6960461 | 0.84 | L3MBTL1 (0.61) | POLBMAPTGAAL3MBTL1PTGS2 | |
| SCHEMBL4262664 | 0.84 | MAPT (0.70) | POLBCA1CA2MAPTKMT2A | |
| SCHEMBL3528003 | 0.84 | PLA2G4B (0.62) | POLBCA1CA2MAPTPTGS2 | |
| SCHEMBL2012060 | 0.83 | MAPT (0.53) | POLBMAPTKMT2AGAAL3MBTL1 | |
| SCHEMBL8407192 | 0.82 | PRSS1 (0.54) | POLBMAPTKMT2AGAAL3MBTL1 | |
| SCHEMBL8409575 | 0.82 | PRSS1 (0.54) | POLBMAPTKMT2AGAAL3MBTL1 | |
| SCHEMBL7283346 | 0.82 | PTGS2 (0.58) | POLBMAPTKMT2AGAAL3MBTL1 | |
| SCHEMBL223169 | 0.81 | PTGS2 (0.57) | POLBMAPTKMT2AGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632020-B1 | Allophanic acid derivatives | ZENECA LTD (GB) | 1997-09-24 | — | — | EP | disclosed |
| US-5494922-A | ANTICOAGULANTS | ZENECA LIMITED (GB) | 1996-02-27 | — | — | US | disclosed |
| US-5463011-A | Allophanic acid derivatives from reacting amines with isocyanate components; anticoagulants; inhibits binding of fibrinogen to glycoprotein IIa/IIIb | ZENECA LIMITED (GB) | 1995-10-31 | — | — | US | disclosed |
| EP-0632020-A1 | Allophanic acid derivatives | ZENECA LIMITED (GB) | 1995-01-04 | — | — | EP | disclosed |