Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809735 | 0.86 | ATM (0.67) | SRD5A2MAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL10547000 | 0.85 | CNR2 (0.49) | ATMTDP1L3MBTL1CNR1CNR2 | |
| SCHEMBL965605 | 0.84 | ATM (0.71) | SRD5A2MAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL10543317 | 0.84 | SRD5A2 (0.58) | SRD5A2ATMTDP1L3MBTL1HPGD | |
| SCHEMBL3177794 | 0.82 | PARP1 (0.59) | SRD5A2MAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL9050342 | 0.80 | SRD5A2 (0.64) | SRD5A2MAPK1L3MBTL1CES2CES1 | |
| SCHEMBL10547863 | 0.80 | ALDH1A1 (0.49) | SRD5A2ATMHPGDCNR2HTT | |
| SCHEMBL9854004 | 0.79 | SRD5A2 (0.70) | SRD5A2MAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL9468917 | 0.79 | MAPK1 (0.64) | SRD5A2MAPK1ATMTDP1L3MBTL1 | |
| SCHEMBL11453670 | 0.79 | ATM (0.57) | SRD5A2MAPK1ATMTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151529-B1 | 5-(AMINO OR SUBSTITUTED AMINO)-1,2,3-TRIAZOLES | MERCK & CO. INC. (US) | 1991-09-18 | — | — | EP | disclosed |