Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 9/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9226154 | 1.00 | REN (0.45) | RENLTA4HCTSKPSEN1PSEN2 | |
| SCHEMBL9226159 | 1.00 | REN (0.45) | RENLTA4HCTSKPSEN1PSEN2 | |
| SCHEMBL1862727 | 0.85 | LTA4H (0.43) | RENLTA4HCTSKPSEN1PSEN2 | |
| SCHEMBL7323220 | 0.85 | REN (0.41) | RENLTA4HCTSK | |
| SCHEMBL7323217 | 0.85 | REN (0.41) | RENLTA4HCTSK | |
| SCHEMBL970651 | 0.82 | REN (0.40) | RENLTA4HCTSKCPB2 | |
| SCHEMBL969489 | 0.82 | REN (0.40) | RENCTSKCPB2 | |
| SCHEMBL972386 | 0.82 | REN (0.40) | RENLTA4HCTSKCPB2 | |
| SCHEMBL7292991 | 0.81 | REN (0.43) | RENLTA4HPSEN1PSEN2APH1B | |
| SCHEMBL9800476 | 0.81 | REN (0.45) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332008-A2 | Peptide-like aminoacid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1989-09-13 | — | — | EP | disclosed |