Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 9/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323220 | 1.00 | REN (0.41) | RENLTA4HMETAP2EPHX1CTSK | |
| SCHEMBL9226159 | 0.85 | REN (0.45) | RENLTA4HCTSK | |
| SCHEMBL7280734 | 0.85 | REN (0.45) | RENLTA4HCTSK | |
| SCHEMBL9226154 | 0.85 | REN (0.45) | RENLTA4HCTSK | |
| SCHEMBL1862727 | 0.80 | LTA4H (0.43) | RENLTA4HMETAP2CTSKKMT2A | |
| SCHEMBL7292991 | 0.79 | REN (0.43) | RENLTA4HEPHX1KMT2A | |
| SCHEMBL9800476 | 0.79 | REN (0.45) | REN | |
| SCHEMBL7429514 | 0.79 | REN (0.43) | RENLTA4H | |
| SCHEMBL9800474 | 0.79 | REN (0.45) | REN | |
| SCHEMBL4972480 | 0.79 | METAP2 (0.43) | RENLTA4HMETAP2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332008-A2 | Peptide-like aminoacid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1989-09-13 | — | — | EP | disclosed |