Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.49 |
| ▸ | CTSK | P43235 | 6/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
| ▸ | PPARG | P37231 | 5/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31230470 | 0.88 | CTSK (0.54) | CTSSCTSKCTSLCTSBPPARA | |
| SCHEMBL31407722 | 0.88 | CTSK (0.54) | CTSSCTSKCTSLCTSBPPARA | |
| SCHEMBL47301 | 0.87 | TGFBR1 (0.52) | CTSSCTSKCTSLCTSBPPARA | |
| SCHEMBL315980 | 0.87 | TGFBR1 (0.52) | CTSSCTSKCTSLCTSBPPARA | |
| SCHEMBL47290 | 0.87 | TGFBR1 (0.52) | CTSSCTSKCTSLCTSBPPARA | |
| Water SCHEMBL23833041 | 0.86 | CTSS (0.54) | CTSSCTSKCTSLCTSBPPARA | |
| Water SCHEMBL31557653 | 0.86 | CTSS (0.54) | CTSSCTSKCTSLCTSBPPARA | |
| Ammonia Solution, Strong SCHEMBL28315164 | 0.86 | CTSK (0.50) | CTSSCTSKCTSLCTSBPPARA | |
| SCHEMBL5025249 | 0.85 | CTSS (0.52) | CTSSCTSKCTSLCTSBPPARA | |
| SCHEMBL5019156 | 0.85 | CTSS (0.52) | CTSSCTSKCTSLCTSBPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0048159-A2 | Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents | UNIVERSITY OF MIAMI (US) | 1982-03-24 | — | — | EP | disclosed |