Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 4/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7280804 | 1.00 | HDAC1 (0.36) | HDAC1HRH3HTTBRAFPTPN1 | |
| SCHEMBL7393684 | 0.94 | HRH3 (0.37) | HDAC1HRH3BRAFPTPN1S1PR1 | |
| SCHEMBL7284346 | 0.88 | HDAC1 (0.39) | HDAC1HRH3PTPN1S1PR1ROCK2 | |
| SCHEMBL7390094 | 0.84 | BAZ2B (0.40) | HRH3 | |
| SCHEMBL8559518 | 0.80 | HRH3 (0.41) | HDAC1HRH3S1PR1POLB | |
| Hydrochloric Acid SCHEMBL8564996 | 0.79 | HRH3 (0.40) | HDAC1HRH3S1PR1POLB | |
| SCHEMBL8559578 | 0.78 | HTR6 (0.42) | HDAC1HRH3S1PR1POLB | |
| Hydrochloric Acid SCHEMBL8566255 | 0.78 | HTR6 (0.41) | HDAC1HRH3S1PR1POLB | |
| SCHEMBL8563370 | 0.77 | ASIC3 (0.40) | HDAC1HRH3S1PR1ROCK2 | |
| SCHEMBL27397736 | 0.77 | MEN1 (0.51) | HDAC1HRH3PTPN1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650424-A | ANTIAGGLOMERANTS USING IMIDAZOLIDINDIONES | DR. KARL THOMAE GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| EP-0503548-B1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | THOMAE GMBH DR K (DE) | 1997-06-04 | — | — | EP | disclosed |
| US-5478942-A | Antiinflammatory agents, antiagglomerants | KARL THOMAE GMBH (DE) | 1995-12-26 | — | — | US | disclosed |
| US-5276049-A | Treatment of thrombosis | DR. KARL THOMAE GMBH (DE) | 1994-01-04 | — | — | US | disclosed |
| EP-0503548-A1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-09-16 | — | — | EP | disclosed |