Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4308489 | 0.81 | AR (0.50) | ALDH1A1KDM4EGAAUSP2PGR | |
| SCHEMBL11619380 | 0.81 | ELANE (0.40) | ALDH1A1HSD17B10HPGDKDM4EGAA | |
| SCHEMBL96290 | 0.79 | CA12 (0.56) | ALDH1A1HPGDMEN1KMT2ACYP3A4 | |
| SCHEMBL1107760 | 0.76 | NQO2 (0.63) | ALDH1A1HSD17B10SMN1; SMN2HPGDKDM4E | |
| SCHEMBL11593518 | 0.75 | ALDH1A1 (0.39) | ALDH1A1HPGDKDM4ECYP3A4USP2 | |
| SCHEMBL7671557 | 0.75 | ALDH1A1 (0.40) | ALDH1A1HSD17B10SMN1; SMN2HPGDKDM4E | |
| SCHEMBL6210428 | 0.75 | ACHE (0.56) | ALDH1A1HPGDKDM4EGAAMEN1 | |
| SCHEMBL11309184 | 0.74 | ALDH1A1 (0.44) | ALDH1A1HSD17B10SMN1; SMN2HPGDKDM4E | |
| SCHEMBL4392239 | 0.73 | TRPV4 (0.50) | ALDH1A1HPGDKDM4ELMNAMEN1 | |
| SCHEMBL7242037 | 0.73 | ALDH1A1 (0.56) | ALDH1A1HSD17B10SMN1; SMN2HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470514-B1 | Carbostyril derivatives and pharmaceutical composition containing the same | OTSUKA PHARMA CO LTD (JP) | 1997-02-19 | — | — | EP | disclosed |
| US-5300513-A | Vasopressin antagonists; vasodilators, hypotensive agents, water diuretics, and platelet agglutination inhibitors | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| EP-0470514-A1 | Carbostyril derivatives and pharmaceutical composition containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-02-12 | — | — | EP | disclosed |