SCHEMBL4308489

SCHEMBL4308489

COc1cc(N(C)C)ccc1C#N

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AR P10275 13/20 0.50
KDM4E B2RXH2 1/20 0.49
USP2 O75604 1/20 0.49
ALDH1A1 P00352 1/20 0.49
PGR P06401 1/20 0.46
IMPDH2 P12268 1/20 0.44
IMPDH1 P20839 1/20 0.44
GABRA1 P14867 1/20 0.43
GABRG2 P18507 1/20 0.43
GABRB3 P28472 1/20 0.43
GABRA3 P34903 1/20 0.43
GABRA2 P47869 1/20 0.43
EGFR P00533 2/20 0.42
POLB P06746 1/20 0.42
GAA P10253 1/20 0.42
HCRTR1 O43613 1/20 0.42
HCRTR2 O43614 1/20 0.42
ERBB2 P04626 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7280865 0.81 ALDH1A1 (0.43) KDM4EUSP2ALDH1A1PGRGAA
SCHEMBL1608900 0.79 AR (0.69) ARKDM4EUSP2ALDH1A1PGR
SCHEMBL2761994 0.77 ALDH1A1 (0.59) ARKDM4EUSP2ALDH1A1PGR
SCHEMBL28573072 0.77 SRC (0.41) ARKDM4EUSP2ALDH1A1IMPDH2
SCHEMBL1107760 0.76 NQO2 (0.63) KDM4EALDH1A1GAA
SCHEMBL24476682 0.75 AR (0.54) ARKDM4EUSP2ALDH1A1PGR
SCHEMBL2614475 0.75 AR (0.69) ARKDM4EUSP2ALDH1A1PGR
SCHEMBL6235064 0.75 AR (0.54) ARKDM4EUSP2ALDH1A1PGR
SCHEMBL4300398 0.75 TSHR (0.45) KDM4EALDH1A1GAA
SCHEMBL1343373 0.73 ALDH1A1 (0.55) ARKDM4EUSP2ALDH1A1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120025651-A High-barrier puncture-resistant food packaging film and preparation method thereof 潮州市潮安区恒昌印制有限公司 2025-05-23 CN claimed
CN-120025651-A High-barrier puncture-resistant food packaging film and preparation method thereof 潮州市潮安区恒昌印制有限公司 2025-05-23 CN disclosed
CN-120025651-A High-barrier puncture-resistant food packaging film and preparation method thereof 潮州市潮安区恒昌印制有限公司 2025-05-23 CN disclosed
US-20090270363-A1 2-Aryl- and 2-Heteroarylthiazolyl Compounds, Methods for Their Preparation and Use Thereof WYETH (US) 2009-10-29 US disclosed
US-20090270363-A1 2-Aryl- and 2-Heteroarylthiazolyl Compounds, Methods for Their Preparation and Use Thereof WYETH (US) 2009-10-29 US disclosed
US-20090270363-A1 2-Aryl- and 2-Heteroarylthiazolyl Compounds, Methods for Their Preparation and Use Thereof WYETH (US) 2009-10-29 US disclosed
WO-2009120826-A1 2-ARYL- AND 2-HETEROARYLTHIAZOLYL COMPOUNDS, METHODS FOR THEIR PREPARATION AND USE THEREOF WYETH (US) 2009-10-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090270363-A1 2-Aryl- and 2-Heteroarylthiazolyl Compounds, Methods for Their Preparation and Use Thereof SEC63, SEC62, SEC22B AR 3181/4885KDM4E 3799/4885USP2 918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.