Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 17/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | CTSE | P14091 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7281017 | 1.00 | CTSS (0.40) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL7286725 | 0.90 | REN (0.42) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL7299470 | 0.89 | CTSS (0.41) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL7281106 | 0.86 | CTSK (0.48) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL7293395 | 0.85 | CTSS (0.39) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL7280387 | 0.83 | CTSS (0.39) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL7298818 | 0.83 | CTSS (0.36) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL7281008 | 0.82 | CTSS (0.40) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL7280900 | 0.82 | CTSS (0.40) | CTSSCTSKRENCTSDCTSE | |
| SCHEMBL7437469 | 0.82 | CTSS (0.50) | CTSSCTSKRENCTSDCTSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0342541-A2 | Retroviral protease inhibitors | ABBOTT LABORATORIES (US) | 1989-11-23 | — | — | EP | disclosed |
| EP-0307837-A2 | Renin-inhibiting peptidyl heterocycles | ABBOTT LABORATORIES (US) | 1989-03-22 | — | — | EP | disclosed |