Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | PRCP | P42785 | 1/20 | 0.46 |
| ▸ | EBP | Q15125 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7282059 | 0.93 | DRD4 (0.55) | DRD2DRD4DRD3HTR1ASIGMAR1 | |
| SCHEMBL7282130 | 0.92 | CYP1A2 (0.60) | DRD2DRD4DRD3CYP1A2CYP3A4 | |
| SCHEMBL11357559 | 0.89 | DRD2 (0.54) | DRD2DRD4DRD3CYP1A2CYP3A4 | |
| SCHEMBL7288835 | 0.88 | HTR1A (0.55) | DRD2DRD3HTR1A | |
| SCHEMBL7279846 | 0.87 | HTR1A (0.60) | DRD2DRD4DRD3HTR1A | |
| SCHEMBL7281777 | 0.87 | DRD4 (0.55) | DRD2DRD4DRD3HTR1ASIGMAR1 | |
| SCHEMBL7282164 | 0.86 | HTR1A (0.58) | DRD2DRD4DRD3HTR1A | |
| SCHEMBL9581524 | 0.86 | KDM4E (0.46) | TDP1 | |
| SCHEMBL7289690 | 0.86 | CYP1A2 (0.54) | DRD2DRD4DRD3CYP1A2CYP3A4 | |
| SCHEMBL7284816 | 0.85 | HTR1A (0.55) | DRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114603-A1 | Indole derivatives | MERCK PATENT GmbH (DE) | 1984-08-01 | — | — | EP | disclosed |