Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7282130 | 0.94 | CYP1A2 (0.60) | CYP1A2CYP3A4HTR1AMAPTCYP2C9 | |
| SCHEMBL7279314 | 0.91 | DRD4 (0.55) | CYP1A2CYP3A4HTR1AMAPTCYP2C9 | |
| SCHEMBL7288835 | 0.90 | HTR1A (0.55) | HTR1ADRD2DRD3HTR7SLC6A4 | |
| SCHEMBL9582547 | 0.90 | TDP1 (0.54) | CYP1A2CYP3A4HTR1AMAPTCYP2C9 | |
| SCHEMBL9582778 | 0.89 | ADRA2A (0.54) | HTR7 | |
| SCHEMBL10648706 | 0.87 | HTR1A (0.46) | CYP1A2CYP3A4HTR1AMAPTCYP2C9 | |
| SCHEMBL7280108 | 0.86 | HTR1A (0.59) | HTR1ADRD2DRD4DRD3HTR7 | |
| SCHEMBL7280976 | 0.86 | DRD2 (0.50) | CYP1A2CYP3A4HTR1AMAPTCYP2C9 | |
| SCHEMBL9581524 | 0.84 | KDM4E (0.46) | TDP1 | |
| SCHEMBL9582549 | 0.83 | ADRA2A (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114603-A1 | Indole derivatives | MERCK PATENT GmbH (DE) | 1984-08-01 | — | — | EP | disclosed |