Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 19/20 | 0.68 |
| ▸ | MTNR1B | P49286 | 13/20 | 0.68 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12964225 | 0.82 | MTNR1A (0.49) | MTNR1AMTNR1B | |
| SCHEMBL1415271 | 0.82 | MTNR1A (0.54) | MTNR1AMTNR1B | |
| SCHEMBL8292402 | 0.82 | MTNR1A (0.62) | MTNR1AMTNR1BDRD3 | |
| SCHEMBL19322908 | 0.81 | MTNR1A (1.00) | MTNR1AMTNR1BDRD3 | |
| SCHEMBL19658437 | 0.81 | MTNR1A (0.65) | MTNR1AMTNR1B | |
| SCHEMBL7273633 | 0.80 | MTNR1A (0.50) | MTNR1AMTNR1B | |
| SCHEMBL8881567 | 0.79 | MTNR1A (0.47) | MTNR1AMTNR1B | |
| SCHEMBL29477258 | 0.79 | MTNR1A (0.55) | MTNR1AMTNR1B | |
| SCHEMBL8291459 | 0.78 | DRD3 (0.58) | MTNR1AMTNR1BDRD3 | |
| SCHEMBL6637708 | 0.78 | MTNR1A (0.49) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8846684-B2 | Arbovirus inhibitors and uses thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2014-09-30 | — | — | US | disclosed |
| EP-0661273-B1 | Indane derivatives and processes for preparing the same | TANABE SEIYAKU CO (JP) | 1999-05-19 | — | — | EP | disclosed |
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5686452-A | PROTECTING FROM ENDOTOXIN SHOCK; TREATMENT OF NEPHRITIS | TANABE SEIYAKU CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |
| US-5605901-A | THERAPY FOR GRAM-NEGATIVE BACTERIA, NEPHRITIS | TANABE SEIYAKU CO., LTD. (JP) | 1997-02-25 | — | — | US | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5543409-A | Indane derivatives for treating endotoxin shock and/or nephritis | TANABE SEIYAKU CO., LTD. (JP) | 1996-08-06 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0661273-A1 | Indane derivative and processes for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1995-07-05 | — | — | EP | disclosed |
| EP-0661274-A1 | Indane derivatives, processes for preparing the same and synthetic intermediate of the same | TANABE SEIYAKU CO., LTD. (JP) | 1995-07-05 | — | — | EP | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |