Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6446069 | 0.87 | MMP2 (0.55) | HTTL3MBTL1POLBALDH1A1LMNA | |
| SCHEMBL12223986 | 0.85 | MMP2 (0.43) | HTTL3MBTL1KCNH2MEN1KMT2A | |
| SCHEMBL12926556 | 0.82 | GABRP (0.46) | HTTL3MBTL1KCNH2MEN1KMT2A | |
| SCHEMBL9672111 | 0.80 | MMP2 (0.50) | L3MBTL1POLBALDH1A1LMNAMMP2 | |
| SCHEMBL25175683 | 0.79 | GABRP (0.50) | HTTL3MBTL1KCNH2MEN1KMT2A | |
| SCHEMBL11214760 | 0.78 | APP (0.50) | L3MBTL1MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL17578918 | 0.78 | KCNH2 (0.55) | HTTL3MBTL1KCNH2MEN1KMT2A | |
| SCHEMBL80450 | 0.77 | CYP2A6 (0.50) | ALDH1A1LMNAMMP2MMP12SMN1; SMN2 | |
| SCHEMBL139332 | 0.77 | ALDH1A1 (0.46) | HTTL3MBTL1KCNH2MEN1KMT2A | |
| SCHEMBL7038938 | 0.76 | CYP2C19 (0.60) | HTTL3MBTL1KCNH2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466790-B | Preparation method of alpha-sulfinylated carbonyl compound | 西北师范大学 | 2024-05-28 | — | — | CN | claimed |
| CN-117466790-A | Preparation method of alpha-sulfinylated carbonyl compound | 西北师范大学 | 2024-01-30 | — | — | CN | claimed |
| CN-118754798-A | Preparation method for preparing propargyl chloride-containing compound by chlorination of phosphorus pentachloride | 上海奥普迪诗化学科技有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-117466790-B | Preparation method of alpha-sulfinylated carbonyl compound | 西北师范大学 | 2024-05-28 | — | — | CN | disclosed |
| US-11912686-B2 | LPA receptor antagonists and uses thereof | GILEAD SCIENCES, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| CN-117466790-A | Preparation method of alpha-sulfinylated carbonyl compound | 西北师范大学 | 2024-01-30 | — | — | CN | disclosed |
| US-20230212151-A1 | LPA RECEPTOR ANTAGONISTS AND USES THEREOF | GILEAD SCIENCES, INC. | 2023-07-06 | — | — | US | disclosed |
| CN-115806471-A | Preparation method for preparing substituted propargyl alcohol by catalyzing paraformaldehyde and alkyne with alkali | 延安大学 | 2023-03-17 | — | — | CN | disclosed |
| CN-110483429-B | Preparation method of 3, 5-disubstituted-4, 5-dihydroisoxazole | 上海应用技术大学 | 2022-10-14 | — | — | CN | disclosed |
| CN-111662147-B | Process for preparing diynes and analogues thereof | 清华大学 | 2021-08-10 | — | — | CN | disclosed |
| CN-109836410-B | (4, 6-diaryl-3, 4-dihydro-2H-thiopyran-3-yl) -aryl ketone and preparation | 上海应用技术大学 | 2021-07-23 | — | — | CN | disclosed |
| US-20080269348-A1 | Novel Arylbicyclo[3.1.0]Hexylamines And Methods And Compositions For Their Preparation And Use | ETHISMOS RESEARCH, INC. | 2008-10-30 | — | — | US | disclosed |
| US-20080269348-A1 | Novel Arylbicyclo[3.1.0]Hexylamines And Methods And Compositions For Their Preparation And Use | ETHISMOS RESEARCH, INC. | 2008-10-30 | — | — | US | disclosed |
| EP-1979311-A2 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | TRANSTECH PHARMA (US) | 2008-10-15 | — | — | EP | disclosed |
| US-20080194696-A1 | Novel Arylbicyclo[3.1.0]Hexylamines And Methods And Compositions For Their Preparation And Use | ETHISMOS RESEARCH, INC. | 2008-08-14 | — | — | US | disclosed |
| US-20080194696-A1 | Novel Arylbicyclo[3.1.0]Hexylamines And Methods And Compositions For Their Preparation And Use | ETHISMOS RESEARCH, INC. | 2008-08-14 | — | — | US | disclosed |
| WO-2007071766-A2 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | TRANSTECH PHARMA (US) | 2007-06-28 | — | — | WO | disclosed |
| WO-1995016215-A1 | NOVEL SUBSTITUTED NAPHTHOPYRANS | PPG INDUSTRIES, INC. (US) | 1995-06-15 | — | — | WO | disclosed |
| US-4996365-A | Preparation of alkyl-substituted cinnamaldehydes | BASF AKTIENGESELLSCHAFT (DE) | 1991-02-26 | — | — | US | disclosed |
| US-4322432-A | Cyclopropanecarboxylic acid alkynyl esters, processes for producing them, and their use as pesticides | CIBA-GEIGY CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194696-A1 | Novel Arylbicyclo[3.1.0]Hexylamines And Methods And Compositions For Their Preparation And Use | HTR2C, HTR1B, HTR3C | HTT 44/4885L3MBTL1 2369/4885KCNH2 619/4885 |
| US-20080269348-A1 | Novel Arylbicyclo[3.1.0]Hexylamines And Methods And Compositions For Their Preparation And Use | HTR2C, HTR1B, HTR3C | HTT 44/4885L3MBTL1 2369/4885KCNH2 619/4885 |
| US-20230212151-A1 | LPA RECEPTOR ANTAGONISTS AND USES THEREOF | LPAR1, LPAR2, LPAR4 | HTT 4717/4885L3MBTL1 2282/4885KCNH2 3203/4885 |
| US-11912686-B2 | LPA receptor antagonists and uses thereof | LPAR1, LPAR2, LPAR4 | HTT 4717/4885L3MBTL1 2282/4885KCNH2 3203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.