Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.38 |
| ▸ | F2 | P00734 | 5/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7276061 | 0.92 | ITGB3 (0.43) | ITGB3ITGA2BF2ITGAVF10 | |
| Hydrochloric Acid SCHEMBL7279790 | 0.89 | F10 (0.42) | ITGB3ITGA2BF2F10LMNA | |
| Hydrochloric Acid SCHEMBL7275045 | 0.87 | ACHE (0.36) | ITGB3ITGA2BF2 | |
| Hydrochloric Acid SCHEMBL7283092 | 0.87 | F10 (0.38) | F2F10 | |
| Hydrochloric Acid SCHEMBL7281006 | 0.86 | ITGB3 (0.44) | ITGB3ITGA2BF2F10ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7283412 | 0.86 | ITGB3 (0.44) | ITGB3ITGA2BF2F10ALDH1A1 | |
| SCHEMBL7273748 | 0.86 | HTR1A (0.38) | ALDH1A1MEN1CYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL7271812 | 0.85 | F2 (0.36) | ITGB3ITGA2BF2F10 | |
| Hydrochloric Acid SCHEMBL7272455 | 0.85 | F10 (0.45) | ITGB3ITGA2BF2F10 | |
| Hydrochloric Acid SCHEMBL7275149 | 0.85 | ITGB3 (0.36) | ITGB3ITGA2BF2ITGAVF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |