SCHEMBL728304

SCHEMBL728304

CNc1ccccc(=O)c1C(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.44
MAPT P10636 3/20 0.44
RAB9A P51151 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
TDP1 Q9NUW8 2/20 0.44
MAPK1 P28482 2/20 0.44
EGFR P00533 1/20 0.44
PABPC1 P11940 1/20 0.44
POLB P06746 4/20 0.39
HSD17B10 Q99714 3/20 0.39
KDM4E B2RXH2 2/20 0.39
ALDH1A1 P00352 2/20 0.39
RECQL P46063 2/20 0.39
USP2 O75604 1/20 0.39
HPGD P15428 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
ATM Q13315 1/20 0.37
NPC1 O15118 2/20 0.36
HTR6 P50406 1/20 0.36
LMNA P02545 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL728295 0.75 POLB (0.52) L3MBTL1MAPTRAB9ASMN1; SMN2TDP1
SCHEMBL2270894 0.72 MAPT (0.37) L3MBTL1MAPTRAB9ASMN1; SMN2TDP1
SCHEMBL24603733 0.71 L3MBTL1 (0.39) L3MBTL1MAPTRAB9ASMN1; SMN2TDP1
SCHEMBL20143730 0.71 L3MBTL1 (0.40) L3MBTL1MAPTRAB9ASMN1; SMN2TDP1
SCHEMBL15934311 0.71 GABRA1 (0.40) L3MBTL1MAPTRAB9ASMN1; SMN2TDP1
SCHEMBL6547618 0.70 CYP3A4 (0.39) L3MBTL1SMN1; SMN2TDP1HSD17B10KDM4E
SCHEMBL2737240 0.69 L3MBTL1 (0.55) L3MBTL1MAPTRAB9ASMN1; SMN2TDP1
SCHEMBL727802 0.68 HDAC4 (0.56) L3MBTL1MAPTRAB9ASMN1; SMN2TDP1
SCHEMBL729860 0.68 HDAC4 (0.52) L3MBTL1MAPTRAB9ASMN1; SMN2TDP1
SCHEMBL29449705 0.68 POLB (0.60) L3MBTL1MAPTRAB9ASMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112837848-A Nano-silver conductive film, preparation method thereof and electronic device 南昌欧菲显示科技有限公司 2021-05-25 CN disclosed
US-8137892-B2 Photobase generator and photocurable resin composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2012-03-20 US disclosed
US-20100151386-A1 PHOTOBASE GENERATOR AND PHOTOCURABLE RESIN COMPOSITION ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-06-17 US disclosed
EP-2093269-A1 PHOTOBASE GENERATOR AND PHOTOCURABLE RESIN COMPOSITION Asahi Kasei Chemicals Corporation (JP) 2009-08-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100151386-A1 PHOTOBASE GENERATOR AND PHOTOCURABLE RESIN COMPOSITION PSMC6, PCNA, POLR2B L3MBTL1 3012/4885MAPT 753/4885RAB9A 787/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.