SCHEMBL728295

SCHEMBL728295

CNc1cccccc1=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.52
HSD17B10 Q99714 3/20 0.52
MAPT P10636 3/20 0.52
TDP1 Q9NUW8 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
ALDH1A1 P00352 2/20 0.52
RECQL P46063 2/20 0.52
KDM4E B2RXH2 2/20 0.52
HPGD P15428 2/20 0.52
USP2 O75604 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
RAB9A P51151 5/20 0.52
NPC1 O15118 4/20 0.52
MAPK1 P28482 2/20 0.47
ALOX12 P18054 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
EGFR P00533 1/20 0.47
PABPC1 P11940 1/20 0.47
HTR6 P50406 1/20 0.47
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL653948 0.76 POLB (0.60) POLBHSD17B10MAPTTDP1L3MBTL1
SCHEMBL29449705 0.76 POLB (0.60) POLBHSD17B10MAPTTDP1L3MBTL1
SCHEMBL24158011 0.76 NPC1 (0.59) HSD17B10MAPTTDP1L3MBTL1ALDH1A1
SCHEMBL728304 0.75 L3MBTL1 (0.44) POLBHSD17B10MAPTTDP1L3MBTL1
SCHEMBL30484919 0.74 POLB (0.57) POLBHSD17B10MAPTTDP1L3MBTL1
Hydrochloric Acid SCHEMBL30384582 0.74 MAPT (0.57) POLBHSD17B10MAPTTDP1L3MBTL1
SCHEMBL728079 0.73 ALDH1A1 (0.63) POLBHSD17B10MAPTALDH1A1KDM4E
SCHEMBL5085669 0.72 NPC1 (0.73) POLBHSD17B10MAPTTDP1L3MBTL1
SCHEMBL5083060 0.72 NPC1 (0.60) POLBHSD17B10MAPTTDP1L3MBTL1
SCHEMBL11449744 0.71 GPR35 (0.52) POLBHSD17B10MAPTTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210289794-A1 COMPOSITIONS AND RELATED METHODS FOR AGRICULTURE FLAGSHIP PIONEERING INNOVATIONS V, INC. 2021-09-23 US disclosed
CN-101553549-B Photobase generator and photocurable resin composition ASAHI KASEI E MATERIALS CORP (JP) 2013-02-20 CN disclosed
US-8137892-B2 Photobase generator and photocurable resin composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2012-03-20 US disclosed
US-20100151386-A1 PHOTOBASE GENERATOR AND PHOTOCURABLE RESIN COMPOSITION ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-06-17 US disclosed
CN-101553549-A Photobase generator and photocurable resin composition ASAHI CHEMICAL CORP (JP) 2009-10-07 CN disclosed
EP-2093269-A1 PHOTOBASE GENERATOR AND PHOTOCURABLE RESIN COMPOSITION Asahi Kasei Chemicals Corporation (JP) 2009-08-26 EP disclosed
US-4183955-A Troponyl-oxamic acid derivatives for treating allergic conditions Ayerst. McKenna & Harrison Limited (CA) 1980-01-15 US disclosed
US-4125625-A ANTIALLERGENS AYERST, MCKENNA & HARRISON LIMITED (CA) 1978-11-14 US disclosed
US-4057556-A ANTIALLERGENS AYERST, MCKENNA & HARRISON LTD. (CA) 1977-11-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100151386-A1 PHOTOBASE GENERATOR AND PHOTOCURABLE RESIN COMPOSITION PSMC6, PCNA, POLR2B POLB 31/4885HSD17B10 3316/4885MAPT 753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.