SCHEMBL7283447

SCHEMBL7283447

C[C@@H]([C]=O)N(C(=O)OCc1ccccc1)c1cccc2ccccc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 2/20 0.39
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 2/20 0.39
HPGD P15428 1/20 0.39
KMT2A Q03164 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A3 Q01959 1/20 0.38
MRGPRX4 Q96LA9 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
CTSL P07711 1/20 0.36
CTSB P07858 1/20 0.36
CTSS P25774 1/20 0.36
CTSK P43235 1/20 0.36
CHRM2 P08172 1/20 0.36
CHRM5 P08912 1/20 0.36
CHRM1 P11229 1/20 0.36
CHRM3 P20309 1/20 0.36
ABCB1 P08183 1/20 0.36
MEN1 O00255 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7142898 0.85 SMPD2 (0.43) CASP1ALDH1A1KDM4EHPGDKMT2A
SCHEMBL7448373 0.85 SMPD2 (0.43) CASP1ALDH1A1KDM4EHPGDKMT2A
SCHEMBL7138305 0.83 CASP1 (0.41) CASP1ALDH1A1KDM4EHPGDKMT2A
SCHEMBL7564622 0.81 ALDH1A1 (0.46) ALDH1A1HPGDKMT2ATDP1SLC6A2
SCHEMBL9826099 0.76 ALDH1A1 (0.44) CASP1ALDH1A1KDM4EHPGDKMT2A
SCHEMBL10725098 0.76 ALDH1A1 (0.42) ALDH1A1HPGDKMT2ATDP1SLC6A2
SCHEMBL4260793 0.75 ABCB1 (0.51) ALDH1A1HPGDKMT2ATDP1SLC6A2
SCHEMBL7285383 0.73 MME (0.46) CASP1ALDH1A1KDM4EHPGDKMT2A
SCHEMBL7285371 0.73 MME (0.46) CASP1ALDH1A1KDM4EHPGDKMT2A
SCHEMBL5696803 0.73 ALDH1A1 (0.47) ALDH1A1KDM4EHPGDKMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0264106-A2 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use Banyu Pharmaceutical Co., Ltd. (JP) 1988-04-20 EP disclosed