Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 3/20 | 0.41 |
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10725098 | 0.91 | ALDH1A1 (0.42) | ALDH1A1KMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL10721118 | 0.87 | RAB9A (0.45) | ALDH1A1KMT2ATDP1MAPTSMN1; SMN2 | |
| SCHEMBL10515353 | 0.82 | ALDH1A1 (0.49) | ALDH1A1KMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL5229233 | 0.82 | ALDH1A1 (0.49) | ALDH1A1KMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL1812242 | 0.82 | ALDH1A1 (0.49) | ALDH1A1KMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL4260793 | 0.82 | ABCB1 (0.51) | ALDH1A1KMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL7283447 | 0.81 | CASP1 (0.39) | ALDH1A1KMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL10556602 | 0.80 | ALDH1A1 (0.46) | ALDH1A1KMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL7292255 | 0.80 | ALDH1A1 (0.46) | ALDH1A1KMT2ATDP1SLC6A2SLC6A3 | |
| SCHEMBL11059329 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KMT2ATDP1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020077455-A1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2002-06-20 | — | — | US | claimed |
| US-20020077455-A1 | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION | 2002-06-20 | — | — | US | disclosed |
| US-5741799-A | ANTICOAGULANTS OF SULFONAMIDO HETEROCYCLIC THROMBIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020077455-A1 | Protease inhibitors | CTSK, CTSZ, CTSG | ALDH1A1 3948/4885KMT2A 2970/4885TDP1 1843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.