SCHEMBL728669

SCHEMBL728669

CCOC(=O)CC(NC[Si](OC)(OCC)OCC)C(=O)OCC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.38
ALDH1A1 P00352 5/20 0.36
TSHR P16473 3/20 0.36
KMT2A Q03164 2/20 0.36
CYP3A4 P08684 2/20 0.36
ALOX15 P16050 2/20 0.36
POLB P06746 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
MGAM O43451 1/20 0.36
GAA P10253 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
CHRM1 P11229 1/20 0.35
ADORA1 P30542 1/20 0.35
HSD17B10 Q99714 1/20 0.35
MAPT P10636 3/20 0.34
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL728606 0.98 L3MBTL1 (0.39) L3MBTL1ALDH1A1TSHRKMT2ACYP3A4
SCHEMBL728627 0.92 L3MBTL1 (0.44) L3MBTL1ALDH1A1TSHRKMT2ACYP3A4
SCHEMBL730300 0.92 L3MBTL1 (0.41) L3MBTL1ALDH1A1TSHRKMT2ACYP3A4
SCHEMBL728589 0.88 L3MBTL1 (0.32) L3MBTL1KMT2APOLBTDP1CAD
SCHEMBL730268 0.87 CA12 (0.30)
SCHEMBL728588 0.87 MAPT (0.32) MAPT
SCHEMBL728425 0.85 ALDH1A1 (0.37) L3MBTL1ALDH1A1TSHRKMT2ACYP3A4
SCHEMBL728349 0.83 ALDH1A1 (0.35) L3MBTL1ALDH1A1TSHRPOLBHSD17B10
SCHEMBL730224 0.80 L3MBTL1 (0.37) L3MBTL1ALDH1A1KMT2APOLBTDP1
SCHEMBL730350 0.80 L3MBTL1 (0.34) L3MBTL1ALDH1A1KMT2APOLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP claimed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US claimed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US claimed
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP disclosed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US disclosed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US disclosed