Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7294857 | 0.80 | MAPKAPK2 (0.50) | EGFRCDC7MAPK9MAPKAPK2MAPT | |
| SCHEMBL25634131 | 0.77 | HTR2C (0.51) | PIK3CGADORA3LTA4HPLA2G2ATRPM8 | |
| SCHEMBL31153238 | 0.77 | HTR2C (0.51) | PIK3CGADORA3LTA4HPLA2G2ATRPM8 | |
| SCHEMBL8110408 | 0.76 | TAAR1 (0.53) | PIK3CGADORA3LTA4HPLA2G2ATRPM8 | |
| Hydrochloric Acid SCHEMBL2243649 | 0.75 | TAAR1 (0.55) | PIK3CGADORA3LTA4HPLA2G2ATRPM8 | |
| SCHEMBL7292567 | 0.74 | MCHR1 (0.52) | ADORA3ALBBCHEACHEBRD4 | |
| SCHEMBL7296072 | 0.74 | BCHE (0.45) | ALBBCHEACHEMCHR1 | |
| SCHEMBL8769400 | 0.73 | PRKCA (0.52) | PIK3CGEGFRADORA3LTA4HPLA2G2A | |
| SCHEMBL7286094 | 0.72 | CDC7 (0.52) | CDC7PIM1PIM2MAPK9MAPKAPK2 | |
| SCHEMBL7294516 | 0.72 | CDC7 (0.52) | CDC7PIM1PIM2MAPK9MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353983-B1 | Lactam derivatives | GLAXO GROUP LTD (GB) | 1996-05-29 | — | — | EP | disclosed |
| US-5183820-A | Useful for treatment of nausea, vomiting, irritable bowel syndrome and dyspepsia | GLAXO GROUP LIMITED (GB) | 1993-02-02 | — | — | US | disclosed |
| EP-0353983-A2 | Lactam derivatives | GLAXO GROUP LIMITED (GB) | 1990-02-07 | — | — | EP | disclosed |