Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.50 |
| ▸ | CDK4 | P11802 | 9/20 | 0.49 |
| ▸ | CCND1 | P24385 | 9/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CCNE2 | O96020 | 5/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.49 |
| ▸ | CDK2 | P24941 | 5/20 | 0.49 |
| ▸ | CAMK2B | Q13554 | 4/20 | 0.49 |
| ▸ | CAMK2G | Q13555 | 4/20 | 0.49 |
| ▸ | CAMK2D | Q13557 | 4/20 | 0.49 |
| ▸ | CAMK2A | Q9UQM7 | 4/20 | 0.49 |
| ▸ | PRKACA | P17612 | 3/20 | 0.49 |
| ▸ | PRKACG | P22612 | 3/20 | 0.49 |
| ▸ | PRKACB | P22694 | 3/20 | 0.49 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.49 |
| ▸ | CDK1 | P06493 | 2/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.49 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8314297 | 0.81 | NQO1 (0.47) | PRKCACHEK1ADORA3MAPTPIK3CG | |
| SCHEMBL5879271 | 0.80 | ADORA3 (0.53) | CHEK1ADORA3MAPTPIK3CGLTA4H | |
| SCHEMBL8599835 | 0.75 | MAOA (0.54) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL27777168 | 0.73 | SRD5A2 (0.56) | ADORA3MAPTPIK3CGLTA4HPLA2G2A | |
| SCHEMBL7284065 | 0.73 | PIK3CG (0.47) | EGFRADORA3MAPTPIK3CGLTA4H | |
| SCHEMBL9348479 | 0.73 | ADORA3 (0.48) | ADORA3MEN1MAPTKMT2APIK3CG | |
| SCHEMBL11115687 | 0.71 | MAPT (0.60) | ADORA3MEN1MAPTKMT2APIK3CG | |
| SCHEMBL23887763 | 0.70 | LTA4H (0.54) | ADORA3MAPTKMT2APIK3CGLTA4H | |
| SCHEMBL8123086 | 0.69 | PRKCA (0.66) | PRKCAEGFRCHEK1CDK4CCND1 | |
| SCHEMBL22566996 | 0.69 | CDK4 (0.83) | PRKCAEGFRCHEK1CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528030-B1 | ANTITUMOR BE-13793C DERIVATIVE | BANYU PHARMA CO LTD (JP) | 1997-09-17 | — | — | EP | disclosed |
| US-5536827-A | ANTITUMOR | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-07-16 | — | — | US | disclosed |
| US-5478813-A | Antitumor substance BE-13793C derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-12-26 | — | — | US | disclosed |
| EP-0528030-A1 | ANTITUMOR BE-13793C DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |