Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 4/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7284598 | 0.99 | ADRB1 (0.46) | ADRB1ADRB3ADRB2ATMLMNA | |
| SCHEMBL7291953 | 0.87 | ATM (0.43) | ADRB1ADRB3ADRB2ATMLMNA | |
| SCHEMBL7283103 | 0.84 | ADRB1 (0.43) | ADRB1ADRB3ADRB2ATMLMNA | |
| SCHEMBL9826041 | 0.81 | ADRB2 (0.43) | ADRB1ADRB3ADRB2ATMLMNA | |
| SCHEMBL9825035 | 0.81 | ADRB2 (0.43) | ADRB1ADRB3ADRB2ATMLMNA | |
| SCHEMBL9825202 | 0.81 | ADRB2 (0.43) | ADRB1ADRB3ADRB2ATMLMNA | |
| SCHEMBL9825260 | 0.81 | ADRB2 (0.42) | ADRB1ADRB3ADRB2ATMLMNA | |
| Hydrochloric Acid SCHEMBL9824900 | 0.81 | ADRB2 (0.44) | ADRB1ADRB3ADRB2ATMLMNA | |
| SCHEMBL1808827 | 0.80 | ADRB1 (0.45) | ADRB1ADRB3ADRB2ATMMAPT | |
| SCHEMBL9824879 | 0.80 | ATM (0.49) | ADRB1ADRB3ADRB2ATMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151006-B1 | DIHYDROPYRIDINE COMPOUNDS, THEIR PRODUCTION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND METHODS OF PRODUCING THESE COMPOSITIONS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-28 | — | — | EP | claimed |