Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7284753 | 0.79 | CLEC4M (0.43) | CNR1CNR2KDM4EALDH1A1HPGD | |
| SCHEMBL9829849 | 0.78 | CLEC4M (0.56) | CNR1CNR2KDM4EALDH1A1HPGD | |
| SCHEMBL7291074 | 0.74 | CLEC4M (0.50) | CNR1CNR2KDM4ECLEC4MMAPT | |
| SCHEMBL7291947 | 0.73 | CLEC4M (0.54) | CNR1CNR2KDM4EALDH1A1HPGD | |
| SCHEMBL62162 | 0.71 | CLEC4M (0.52) | CNR1CNR2KDM4EALDH1A1HPGD | |
| SCHEMBL10839866 | 0.70 | KDM4E (0.65) | CNR1CNR2KDM4EALDH1A1HPGD | |
| SCHEMBL397393 | 0.69 | CLEC4M (0.52) | CNR1CNR2KDM4EALDH1A1HPGD | |
| SCHEMBL7291746 | 0.68 | CLEC4M (0.51) | CNR1CNR2KDM4EALDH1A1HPGD | |
| SCHEMBL2432859 | 0.66 | ADORA3 (0.43) | KDM4EALDH1A1HPGDMAPTCYP3A4 | |
| SCHEMBL7284683 | 0.66 | CYP1A2 (0.59) | KDM4EALDH1A1HPGDCLEC4MMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343574-B1 | 4(1H)-quinolone derivatives | KIRIN BREWERY (JP) | 1994-07-27 | — | — | EP | claimed |
| EP-0343574-B1 | 4(1H)-quinolone derivatives | KIRIN BREWERY (JP) | 1994-07-27 | — | — | EP | disclosed |
| US-5081121-A | Cardiotonic agents | KIRIN BEER KABUSHIKI KAISHA (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0343574-A1 | 4(1H)-quinolone derivatives | KIRIN BEER KABUSHIKI KAISHA (JP) | 1989-11-29 | — | — | EP | disclosed |