SCHEMBL2432859

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2430280	0.96	ADORA3 (0.42)	ADORA3IDO1ALDH1A1KDM4ECYP3A4
	SCHEMBL1136007	0.90	ADORA3 (0.40)	ADORA3IDO1ALDH1A1KDM4ECYP3A4
	SCHEMBL2431867	0.87	PDE4B (0.37)	ADORA3IDO1
	SCHEMBL2433158	0.86	ALDH1A1 (0.39)	IDO1ALDH1A1KDM4ECYP3A4HSD17B10
	SCHEMBL2437576	0.86	MET (0.38)	METKDRAXLTDP1PDGFRB
	SCHEMBL2430302	0.85	ALDH1A1 (0.46)	IDO1ALDH1A1KDM4ECYP3A4HSD17B10
	SCHEMBL2433750	0.83	XDH (0.41)	IDO1ALDH1A1KDM4ECYP3A4HSD17B10
	SCHEMBL2432159	0.82	NPC1 (0.37)	IDO1ALDH1A1KDM4ECYP3A4HSD17B10
	SCHEMBL2432114	0.82	NPC1 (0.37)	IDO1ALDH1A1KDM4ECYP3A4HSD17B10
	SCHEMBL2432282	0.82	NPC1 (0.37)	IDO1ALDH1A1KDM4ECYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.