Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7284072 | 0.93 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTNAMPTCYP19A1 | |
| SCHEMBL7282551 | 0.90 | ABCB1 (0.44) | ALDH1A1LMNAMAPTKDM4EPOLB | |
| SCHEMBL7274151 | 0.90 | ABCB1 (0.44) | ALDH1A1LMNAMAPTKDM4EPOLB | |
| SCHEMBL7281268 | 0.90 | ABCB1 (0.44) | ALDH1A1LMNAMAPTKDM4EPOLB | |
| Hydrochloric Acid SCHEMBL7273834 | 0.89 | ITGB3 (0.43) | ALDH1A1LMNAMAPTNR1H4SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7272660 | 0.89 | ITGB3 (0.43) | ALDH1A1LMNAMAPTNR1H4SMN1; SMN2 | |
| SCHEMBL7276118 | 0.88 | ALDH1A1 (0.40) | ALDH1A1LMNAMAPTNAMPTCYP19A1 | |
| SCHEMBL7274141 | 0.88 | ALDH1A1 (0.40) | ALDH1A1LMNAMAPTNAMPTCYP19A1 | |
| SCHEMBL7284861 | 0.87 | MAPT (0.41) | ALDH1A1LMNAMAPTNAMPTCYP19A1 | |
| SCHEMBL7274458 | 0.87 | ABCB1 (0.43) | ALDH1A1LMNAMAPTNAMPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |