Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.55 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.48 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.46 |
| ▸ | F2R | P25116 | 2/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.40 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.40 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.40 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.40 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6069474 | 0.80 | PKM (0.47) | ITGB3ITGA2BGNAO1GNAI3GNAI1 | |
| SCHEMBL7287283 | 0.79 | ITGB3 (0.65) | ITGB3ITGA2BGNAO1GNAI3GNAI1 | |
| SCHEMBL7452238 | 0.78 | ITGB3 (0.63) | ITGB3ITGA2BGNAO1GNAI3GNAI1 | |
| SCHEMBL24754066 | 0.78 | MAPT (0.47) | GNAO1GNAI3GNAI1 | |
| SCHEMBL17440475 | 0.78 | ITGB3 (0.67) | ITGB3ITGA2BGNAO1GNAI3GNAI1 | |
| SCHEMBL3087409 | 0.78 | GNAI3 (0.45) | ITGB3ITGA2BGNAO1GNAI3GNAI1 | |
| SCHEMBL7276429 | 0.77 | ITGB3 (0.70) | ITGB3ITGA2BGNAO1GNAI3GNAI1 | |
| SCHEMBL8473840 | 0.77 | ITGB3 (0.42) | ITGB3ITGA2BGNAO1SLC6A1GABRA5 | |
| Hydrochloric Acid SCHEMBL29119874 | 0.76 | ITGB3 (0.65) | ITGB3ITGA2BGNAO1GNAI3GNAI1 | |
| SCHEMBL6621587 | 0.76 | ITGB3 (0.46) | ITGB3ITGA2BGNAO1GNAI3GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528369-A2 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-02-24 | — | — | EP | claimed |
| US-5455348-A | Anticoagulants | Thomae, Karl (DE) | 1995-10-03 | — | — | US | disclosed |
| EP-0528369-A2 | Cyclic imino derivatives, pharmaceutical compositions containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1993-02-24 | — | — | EP | disclosed |