Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 6/20 | 0.50 |
| ▸ | DRD4 | P21917 | 6/20 | 0.50 |
| ▸ | DRD3 | P35462 | 6/20 | 0.50 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7286101 | 0.83 | OPRM1 (0.56) | OPRM1OPRK1OPRL1DRD2DRD4 | |
| SCHEMBL7297641 | 0.83 | ALDH1A1 (0.55) | OPRM1OPRK1OPRL1DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL8824510 | 0.82 | ALDH1A1 (0.54) | OPRM1OPRK1OPRL1DRD2DRD4 | |
| SCHEMBL7296367 | 0.81 | OPRM1 (0.57) | OPRM1OPRK1OPRL1DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL7287430 | 0.79 | DRD2 (0.51) | OPRM1OPRK1OPRL1DRD2DRD4 | |
| SCHEMBL20685543 | 0.77 | ALDH1A1 (0.61) | OPRM1OPRK1OPRL1DRD2DRD4 | |
| SCHEMBL7295422 | 0.77 | OPRM1 (0.63) | OPRM1OPRK1OPRL1DRD2DRD4 | |
| SCHEMBL7297914 | 0.74 | OPRM1 (0.58) | OPRM1OPRK1OPRL1DRD2DRD4 | |
| SCHEMBL7296315 | 0.74 | OPRM1 (0.60) | OPRM1OPRK1OPRL1DRD2DRD4 | |
| SCHEMBL7287197 | 0.73 | OPRM1 (0.58) | OPRM1OPRK1OPRL1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652247-A | VASOPRESSIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD (JP) | 1997-07-29 | — | — | US | disclosed |
| US-5436254-A | Vaopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |