Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 3/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.53 |
| ▸ | CCR3 | P51677 | 7/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8824510 | 0.99 | ALDH1A1 (0.54) | ALDH1A1DRD2DRD4DRD3OPRM1 | |
| Hydrochloric Acid SCHEMBL7286101 | 0.91 | OPRM1 (0.56) | ALDH1A1DRD2DRD4DRD3OPRM1 | |
| SCHEMBL7296367 | 0.87 | OPRM1 (0.57) | DRD2DRD4DRD3OPRM1OPRK1 | |
| SCHEMBL7295422 | 0.85 | OPRM1 (0.63) | DRD2DRD4DRD3OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL7297984 | 0.85 | DRD2 (0.54) | DRD2DRD4DRD3OPRM1OPRK1 | |
| SCHEMBL7285183 | 0.83 | OPRM1 (0.52) | ALDH1A1DRD2DRD4DRD3OPRM1 | |
| SCHEMBL20685543 | 0.83 | ALDH1A1 (0.61) | ALDH1A1DRD2DRD4DRD3OPRM1 | |
| Hydrochloric Acid SCHEMBL7287647 | 0.82 | OPRM1 (0.56) | DRD2DRD4DRD3OPRM1OPRK1 | |
| SCHEMBL3995292 | 0.81 | ALDH1A1 (0.54) | ALDH1A1DRD2DRD4DRD3OPRM1 | |
| SCHEMBL7297914 | 0.80 | OPRM1 (0.58) | DRD2DRD4DRD3OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |