Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 18/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | LAP3 | P28838 | 1/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.42 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285402 | 1.00 | CPB2 (0.47) | CPB2ANPEPLAP3ERAP2ERAP1 | |
| SCHEMBL7284748 | 0.86 | CPB2 (0.49) | CPB2 | |
| SCHEMBL7284754 | 0.86 | CPB2 (0.49) | CPB2 | |
| SCHEMBL10718807 | 0.85 | CPB2 (0.48) | CPB2 | |
| SCHEMBL10718805 | 0.85 | CPB2 (0.48) | CPB2 | |
| SCHEMBL9647220 | 0.77 | ANPEP (0.65) | ANPEPLAP3ERAP2ERAP1LNPEP | |
| SCHEMBL30438211 | 0.74 | CPB2 (0.63) | CPB2 | |
| Hydrochloric Acid SCHEMBL10718561 | 0.73 | ACE2 (0.48) | ANPEPERAP2ERAP1LNPEP | |
| SCHEMBL7306963 | 0.73 | CPB2 (0.48) | CPB2 | |
| SCHEMBL10718337 | 0.73 | MMP3 (0.51) | CPB2ERAP2ERAP1LNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210545-A2 | Phosphorous containing enzyme inhibitors | MERCK & CO. INC. (US) | 1987-02-04 | — | — | EP | disclosed |
| EP-0209897-A2 | Peptide enzyme inhibitors | MERCK & CO. INC. (US) | 1987-01-28 | — | — | EP | disclosed |