Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 3/20 | 0.65 |
| ▸ | LAP3 | P28838 | 2/20 | 0.65 |
| ▸ | DPEP1 | P16444 | 6/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 5/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.42 |
| ▸ | IL1RN | P18510 | 2/20 | 0.42 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9646994 | 0.88 | DPEP1 (0.49) | ANPEPLAP3DPEP1ERAP2 | |
| SCHEMBL7277423 | 0.86 | ANPEP (0.47) | ANPEPLAP3DPEP1ERAP2ERAP1 | |
| Bromide SCHEMBL10716158 | 0.85 | ANPEP (0.46) | ANPEPLAP3DPEP1ERAP2ERAP1 | |
| SCHEMBL9645168 | 0.83 | METAP1 (0.54) | ANPEPLAP3DPEP1ERAP2 | |
| SCHEMBL9646181 | 0.80 | ALDH1A1 (0.46) | ANPEPLAP3DPEP1ERAP2 | |
| SCHEMBL9246018 | 0.77 | LTA4H (0.44) | ANPEPLAP3DPEP1ERAP2 | |
| SCHEMBL7285396 | 0.77 | CPB2 (0.47) | ANPEPLAP3ERAP2ERAP1LNPEP | |
| SCHEMBL7285402 | 0.77 | CPB2 (0.47) | ANPEPLAP3ERAP2ERAP1LNPEP | |
| SCHEMBL9647093 | 0.76 | ALDH1A1 (0.47) | ANPEPLAP3DPEP1ERAP2ERAP1 | |
| SCHEMBL9697243 | 0.75 | LAP3 (0.77) | ANPEPLAP3ERAP2ERAP1IL1RN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147867-A | Bactericides, (carba)penicillins | MERCK & CO., INC. (US) | 1992-09-15 | — | — | US | disclosed |
| US-5145990-A | Dehydropeptidase, carbapenicillin potentiation | MERCK & CO., INC. (US) | 1992-09-08 | — | — | US | disclosed |
| US-4962097-A | IN COMBINATION WITH A CARBAPENEM OR PENEM ANTIBIOTIC | MERCK & CO., INC. (US) | 1990-10-09 | — | — | US | disclosed |
| EP-0366469-A2 | Phosphorus containing enzyme inhibitors | MERCK & CO. INC. (US) | 1990-05-02 | — | — | EP | disclosed |