Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 4/20 | 0.51 |
| ▸ | MMP1 | P03956 | 2/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.49 |
| ▸ | CPA1 | P15085 | 4/20 | 0.47 |
| ▸ | CPA2 | P48052 | 4/20 | 0.47 |
| ▸ | CPA4 | Q9UI42 | 4/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.46 |
| ▸ | REN | P00797 | 2/20 | 0.45 |
| ▸ | CPB1 | P15086 | 1/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.43 |
| ▸ | IL1RN | P18510 | 2/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10716135 | 0.87 | MMP3 (0.51) | MMP3MMP1MMP2CPA1CPA2 | |
| SCHEMBL10716071 | 0.84 | ACE2 (0.67) | ACE2 | |
| SCHEMBL7283423 | 0.78 | ACE2 (0.60) | ACE2 | |
| Hydrochloric Acid SCHEMBL10718561 | 0.76 | ACE2 (0.48) | MMP3MMP1MMP2CPA1CPA2 | |
| SCHEMBL10718394 | 0.75 | ACE2 (0.58) | ACE2 | |
| SCHEMBL7029711 | 0.73 | LTA4H (0.60) | MMP3MMP1MMP2CPA1ACE2 | |
| SCHEMBL7429175 | 0.73 | REN (0.63) | MMP3MMP1MMP2REN | |
| SCHEMBL7285402 | 0.73 | CPB2 (0.47) | CPB2ERAP2ERAP1LNPEP | |
| SCHEMBL7285396 | 0.73 | CPB2 (0.47) | CPB2ERAP2ERAP1LNPEP | |
| SCHEMBL7283367 | 0.73 | ACE2 (0.51) | MMP2ACE2RENERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210545-A2 | Phosphorous containing enzyme inhibitors | MERCK & CO. INC. (US) | 1987-02-04 | — | — | EP | claimed |
| EP-0210545-A2 | Phosphorous containing enzyme inhibitors | MERCK & CO. INC. (US) | 1987-02-04 | — | — | EP | disclosed |