Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1826516 | 0.86 | MAPT (0.61) | MAPTHTTKDM4ETSHRHPGD | |
| SCHEMBL9396474 | 0.84 | MAPT (0.42) | MAPTHTTKDM4EHSD17B10TSHR | |
| SCHEMBL9511988 | 0.84 | L3MBTL1 (0.46) | KDM4EHPGDALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL15486368 | 0.84 | KDM4E (0.61) | HTTKDM4EHSD17B10TSHRHPGD | |
| SCHEMBL2863138 | 0.84 | MAPT (0.44) | MAPTHTTKDM4EHSD17B10TSHR | |
| SCHEMBL6805636 | 0.84 | MAPT (0.48) | MAPTHTTKDM4EHSD17B10HPGD | |
| SCHEMBL7913533 | 0.81 | CA12 (0.55) | MAPTKDM4EHSD17B10TSHRHPGD | |
| SCHEMBL4267637 | 0.81 | CHRM2 (0.53) | MAPTKDM4EALDH1A1CA2CA9 | |
| SCHEMBL11736595 | 0.80 | ALDH1A1 (0.48) | MAPTHTTKDM4ETSHRHPGD | |
| Hydrochloric Acid SCHEMBL4898132 | 0.80 | CHRM2 (0.56) | MAPTKDM4EALDH1A1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594855-B1 | SIGNALLING COMPOUNDS FOR USE IN METHODS OF DETECTING HYDROGEN PEROXIDE | LUMIGEN INC (US) | 2014-01-22 | — | — | EP | disclosed |
| EP-1509601-B1 | FLUORESCENT DETECTION OF PEROXIDASE ENZYMES | LUMIGEN INC (US) | 2012-12-05 | — | — | EP | disclosed |
| EP-2305690-B1 | Signalling compounds for use in methods of detecting hydrogen peroxide | LUMIGEN INC (US) | 2012-08-29 | — | — | EP | disclosed |
| US-8137990-B2 | Compositions for chemiluminescent detection of hydrogen peroxide | LUMIGEN, INC. (US) | 2012-03-20 | — | — | US | disclosed |
| EP-2305690-A1 | Signalling compounds for use in methods of detecting hydrogen peroxide | LUMIGEN, INC. (US) | 2011-04-06 | — | — | EP | disclosed |
| US-7704752-B2 | Signalling compounds for use in methods of detecting hydrogen peroxide | LUMIGEN, INC. (US) | 2010-04-27 | — | — | US | disclosed |
| US-20100055800-A1 | Compositions for Chemiluminescent Detection of Hydrogen Peroxide | LUMIGEN, INC. (US) | 2010-03-04 | — | — | US | disclosed |
| US-20080261318-A1 | Signalling Compounds For Use In Methods Of Detecting Hydrogen Peroxide | LUMIGEN, INC. (US) | 2008-10-23 | — | — | US | disclosed |
| US-7390670-B2 | Signalling compounds and methods for detecting hydrogen peroxide | LUMIGEN, INC. (US) | 2008-06-24 | — | — | US | disclosed |
| US-6919463-B2 | Signalling compounds for use in methods of detecting hydrogen peroxide | LUMIGEN, INC. (US) | 2005-07-19 | — | — | US | disclosed |
| US-6897036-B2 | Fluorescent detection of peroxidase enzymes | LUMIGEN, INC. (US) | 2005-05-24 | — | — | US | disclosed |
| US-20040171098-A1 | Signalling compounds for use in methods of detecting hydrogen peroxide | LUMIGEN INC. | 2004-09-02 | — | — | US | disclosed |
| US-20040166539-A1 | Signalling compounds and methods for detecting hydrogen peroxide | LUMIGEN, INC. | 2004-08-26 | — | — | US | disclosed |
| US-20030232405-A1 | Fluorescent detection of peroxidase enzymes | LUMIGEN INC. | 2003-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171098-A1 | Signalling compounds for use in methods of detecting hydrogen peroxide | LPO, HAO2, HAO1 | MAPT 4885/4885HTT 4773/4885KDM4E 4844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.