Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 1/20 | 0.50 |
| ▸ | GNPAT | O15228 | 1/20 | 0.45 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
| ▸ | PAM | P19021 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | FCER2 | P06734 | 1/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.39 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.39 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.39 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.39 |
| ▸ | PSMD3 | O43242 | 1/20 | 0.39 |
| ▸ | PSMC3 | P17980 | 1/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.39 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.39 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.39 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285504 | 1.00 | CTSS (0.50) | CTSSCTSKGNPATRENPAM | |
| SCHEMBL7286963 | 0.88 | PSMB5 (0.51) | CTSSRENMMP1FCER2PSMB5 | |
| SCHEMBL7286971 | 0.88 | PSMB5 (0.51) | CTSSRENMMP1FCER2PSMB5 | |
| SCHEMBL7268466 | 0.87 | CTSS (0.56) | CTSSCTSKRENHDAC8CTSL | |
| SCHEMBL7296225 | 0.87 | CTSS (0.56) | CTSSCTSKRENHDAC8CTSL | |
| SCHEMBL11762672 | 0.87 | MMP1 (0.51) | CTSSCTSKGNPATMMP1FCER2 | |
| SCHEMBL7286303 | 0.87 | TACR1 (0.54) | CTSSCTSKTACR1CTSLCTSB | |
| SCHEMBL7286309 | 0.87 | TACR1 (0.54) | CTSSCTSKTACR1CTSLCTSB | |
| SCHEMBL7292510 | 0.87 | CTSL (0.40) | MMP1FCER2CTSL | |
| SCHEMBL7292514 | 0.87 | CTSL (0.40) | MMP1FCER2CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0264106-B1 | 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use | BANYU PHARMA CO LTD (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-4851387-A | RENIN INHIBITORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| EP-0264106-A2 | 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use | Banyu Pharmaceutical Co., Ltd. (JP) | 1988-04-20 | — | — | EP | disclosed |