Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.60 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 10/20 | 0.58 |
| ▸ | MAOA | P21397 | 8/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11565649 | 0.87 | RAB9A (0.61) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL13657349 | 0.86 | ALDH1A1 (0.57) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL30963763 | 0.82 | ALDH1A1 (0.62) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL17237762 | 0.82 | ALDH1A1 (0.62) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL28990315 | 0.81 | MAOB (0.60) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9057896 | 0.81 | ALDH1A1 (0.60) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL28477922 | 0.81 | ALDH1A1 (0.60) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL29640433 | 0.78 | RAB9A (0.67) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL28172130 | 0.78 | RAB9A (0.67) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL1572774 | 0.78 | MAOB (0.71) | RAB9ANPC1ALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0246633-B1 | Trans-benzopyran-[4,3-b]-1,4-oxazine derivatives | WARNER-LAMBERT COMPANY (US) | 1991-01-02 | — | — | EP | disclosed |
| US-4792548-A | Trans-benzopyran-(4,3-b)-1,4-oxazine derivatives, intermediates and pharmaceutical use | WARNER-LAMBERT COMPANY (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0246633-A1 | Trans-benzopyran-[4,3-b]-1,4-oxazine derivatives | WARNER-LAMBERT COMPANY (US) | 1987-11-25 | — | — | EP | disclosed |
| US-4288450-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1981-09-08 | — | — | US | disclosed |
| US-4216155-A | 3-GLYCOLOYLAMINO-4-OXO-4H-1-BENZOPYRAN; ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1980-08-05 | — | — | US | disclosed |
| EP-0000488-A1 | 3-Oxaloamino-4-oxo-4H-1-benzopyrane compounds, process for their preparation and their pharmaceutical use | CIBA-GEIGY AG (CH) | 1979-02-07 | — | — | EP | disclosed |