Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 8/20 | 0.58 |
| ▸ | MAOB | P27338 | 8/20 | 0.58 |
| ▸ | XDH | P47989 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285550 | 0.87 | RAB9A (0.60) | RAB9ANPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL2109107 | 0.81 | RAB9A (0.61) | RAB9ANPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL28990293 | 0.81 | RAB9A (0.61) | RAB9ANPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL5242625 | 0.81 | RAB9A (0.61) | RAB9ANPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL29817357 | 0.79 | CYP11B1 (0.67) | RAB9ANPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL6967032 | 0.78 | MAOA (0.71) | RAB9ANPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL571576 | 0.78 | XDH (0.84) | RAB9ANPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL29953101 | 0.78 | MAOA (0.71) | RAB9ANPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL21591546 | 0.77 | CYP11B1 (0.64) | RAB9ANPC1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL11550870 | 0.77 | RAB9A (0.60) | RAB9ANPC1MAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000488-A1 | 3-Oxaloamino-4-oxo-4H-1-benzopyrane compounds, process for their preparation and their pharmaceutical use | CIBA-GEIGY AG (CH) | 1979-02-07 | — | — | EP | disclosed |
| US-4076729-A | (4-Oxo-4H-1-benzopyran-3-yl)aminooxoacetic acids and their derivatives | WARNER-LAMBERT COMPANY (US) | 1978-02-28 | — | — | US | disclosed |
| US-4066655-A | 4,10-Dihydro-4,10-dioxo-1H-1-benzopyrano[3,2-b]pyridine-3-carboxylic acids, salts and esters | WARNER-LAMBERT COMPANY (US) | 1978-01-03 | — | — | US | disclosed |
| US-4046769-A | 4,10-Dihydro-4,10-dioxo-1H-1-benzopyrano[3,2-b]pyridine-2-carboxylic acids and esters | WARNER-LAMBERT COMPANY (US) | 1977-09-06 | — | — | US | disclosed |