Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.46 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA4 | P22748 | 3/20 | 0.45 |
| ▸ | CA7 | P43166 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL357341 | 1.00 | ALDH1A1 (0.52) | ALDH1A1ALOX15GRIK1GRIA1GRIA2 | |
| SCHEMBL891695 | 1.00 | ALDH1A1 (0.52) | ALDH1A1ALOX15GRIK1GRIA1GRIA2 | |
| Acetaldehyde SCHEMBL11678453 | 0.96 | ALDH1A1 (0.48) | ALDH1A1ALOX15GRIK1GRIA1GRIA2 | |
| SCHEMBL70202 | 0.87 | ALDH1A1 (0.62) | ALDH1A1ALOX15GRIK1GRIA1GRIA2 | |
| SCHEMBL8902281 | 0.87 | ALDH1A1 (0.62) | ALDH1A1ALOX15GRIK1GRIA1GRIA2 | |
| SCHEMBL70201 | 0.87 | ALDH1A1 (0.62) | ALDH1A1ALOX15GRIK1GRIA1GRIA2 | |
| SCHEMBL23226919 | 0.83 | LMNA (0.41) | ALDH1A1ALOX15LMNAKDM4ECA12 | |
| SCHEMBL27715967 | 0.83 | BCHE (0.39) | ALDH1A1ALOX15GRIK1GRIA1GRIA2 | |
| SCHEMBL2517175 | 0.83 | ALDH1A1 (0.56) | ALDH1A1ALOX15LMNAKDM4ECA12 | |
| SCHEMBL9497002 | 0.82 | AKR1C3 (0.52) | ALDH1A1MAPTKMT2APOLBAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4738738-B2 | — | — | 2011-08-03 | — | — | JP | claimed |
| US-4544767-A | HYDROGENATION CATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1985-10-01 | — | — | US | claimed |
| EP-1567488-A1 | HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | GLAXO GROUP LIMITED (GB) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004050619-A1 | HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | GLAXO GROUP LIMITED (GB) | 2004-06-17 | — | — | WO | disclosed |
| US-4544767-A | HYDROGENATION CATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1985-10-01 | — | — | US | disclosed |