Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.46 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA4 | P22748 | 3/20 | 0.45 |
| ▸ | CA7 | P43166 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL728576 | 1.00 | ALDH1A1 (0.52) | ALDH1A1ALOX15GRIK1GRIA1GRIA2 | |
| SCHEMBL357341 | 1.00 | ALDH1A1 (0.52) | ALDH1A1ALOX15GRIK1GRIA1GRIA2 | |
| Acetaldehyde SCHEMBL11678453 | 0.96 | ALDH1A1 (0.48) | ALDH1A1ALOX15GRIK1GRIA1GRIA2 | |
| SCHEMBL70202 | 0.87 | ALDH1A1 (0.62) | ALDH1A1ALOX15GRIK1GRIA1GRIA2 | |
| SCHEMBL8902281 | 0.87 | ALDH1A1 (0.62) | ALDH1A1ALOX15GRIK1GRIA1GRIA2 | |
| SCHEMBL70201 | 0.87 | ALDH1A1 (0.62) | ALDH1A1ALOX15GRIK1GRIA1GRIA2 | |
| SCHEMBL23226919 | 0.83 | LMNA (0.41) | ALDH1A1ALOX15LMNAKDM4ECA12 | |
| SCHEMBL27715967 | 0.83 | BCHE (0.39) | ALDH1A1ALOX15GRIK1GRIA1GRIA2 | |
| SCHEMBL2517175 | 0.83 | ALDH1A1 (0.56) | ALDH1A1ALOX15LMNAKDM4ECA12 | |
| SCHEMBL9497002 | 0.82 | AKR1C3 (0.52) | ALDH1A1MAPTKMT2APOLBAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10329575-B2 | Regulatory sequence for plants | CERES, INC. (US) | 2019-06-25 | — | — | US | disclosed |
| US-20180223303-A1 | SEQUENCE-DETERMINED DNA FRAGMENTS AND CORRESPONDING POLYPEPTIDES ENCODED THEREBY | CERES INC (US) | 2018-08-09 | — | — | US | disclosed |
| US-20170037426-A1 | Sequence-determined DNA fragments and corresponding polypeptides encoded thereby | ALEXANDROV NICKOLAI (US) | 2017-02-09 | — | — | US | disclosed |
| US-20160076046-A1 | PROMOTER, PROMOTER CONTROL ELEMENTS, AND COMBINATIONS, AND USES THEREOF | CERES, INC. (US) | 2016-03-17 | — | — | US | disclosed |
| US-9029523-B2 | Promoter, promoter control elements, and combinations, and uses thereof | CERES, INC. (US) | 2015-05-12 | — | — | US | disclosed |
| US-20150033417-A9 | Promoter, promoter control elements, and combinations, and uses thereof | ALEXANDROV NICKOLAI (US) | 2015-01-29 | — | — | US | disclosed |
| US-8877916-B2 | Promoter, promoter control elements, and combinations, and uses thereof | CERES, INC. (US) | 2014-11-04 | — | — | US | disclosed |
| US-8273773-B2 | Heterocyclic antiviral compounds | ROCHE PALO ALTO LLC (US) | 2012-09-25 | — | — | US | disclosed |
| US-20120159672-A1 | Sequence-determined DNA fragments and corresponding polypeptides encoded thereby | CERES, INC. | 2012-06-21 | — | — | US | disclosed |
| US-20120084885-A1 | Promoter, promoter control elements, and combinations, and uses thereof | ALEXANDROV NICKOLAI (US) | 2012-04-05 | — | — | US | disclosed |
| US-20100037355-A1 | SEQUENCE-DETERMINED DNA FRAGMENTS AND CORRESPONDING POLYPEPTIDES ENCODED THEREBY | CERES, INC (US) | 2010-02-11 | — | — | US | disclosed |
| US-20100021423-A1 | Heterocyclic antiviral compounds | ROCHE PALO ALTO LLC | 2010-01-28 | — | — | US | disclosed |
| US-7635572-B2 | Methods for conducting assays for enzyme activity on protein microarrays | Life Technologies Corporation (US) | 2009-12-22 | — | — | US | disclosed |
| US-20090265815-A1 | Sequence-determined DNA fragments and corresponding polypeptides encoded therapy | ALEXANDROV NICKOLAI | 2009-10-22 | — | — | US | disclosed |
| US-20070214517-A1 | Sequence-determined DNA fragments and corresponding polypeptides encoded thereby | CERES, INC. (US) | 2007-09-13 | — | — | US | disclosed |
| US-20060150283-A1 | Sequence-determined DNA fragments and corresponding polypeptides encoded thereby | ALEXANDROV NICKOLAI | 2006-07-06 | — | — | US | disclosed |
| US-20060048240-A1 | Sequence-determined DNA fragments and corresponding polypeptides encoded thereby | ALEXANDROV NICKOLAI | 2006-03-02 | — | — | US | disclosed |
| CN-1646496-A | Novel tricyclic imidazoline derivatives, process for their preparation and their use as medicaments | PF MEDICAMENT (FR) | 2005-07-27 | — | — | CN | disclosed |
| US-20050118665-A1 | Methods for conducting assays for enzyme activity on protein microarrays | PROTOMETRIX, INC. | 2005-06-02 | — | — | US | disclosed |
| US-20050107455-A1 | Novel tricycloimidazoline derivatives method for production and use thereof as medicaments | PIERRE FABRE MEDICAMENT (FR) | 2005-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107455-A1 | Novel tricycloimidazoline derivatives method for production and use thereof as medicaments | CYP4F3, HRH4, SLCO1B3 | ALDH1A1 3053/4885ALOX15 3955/4885GRIK1 1807/4885 |
| US-20170037426-A1 | Sequence-determined DNA fragments and corresponding polypeptides encoded thereby | RNGTT, CPSF1, CPSF6 | ALDH1A1 4769/4885ALOX15 4864/4885GRIK1 4322/4885 |
| US-20150033417-A9 | Promoter, promoter control elements, and combinations, and uses thereof | RNGTT, GTF3C5, GTF3C1 | ALDH1A1 4635/4885ALOX15 4753/4885GRIK1 4273/4885 |
| US-20120084885-A1 | Promoter, promoter control elements, and combinations, and uses thereof | RNGTT, GTF3C5, GTF3C1 | ALDH1A1 4633/4885ALOX15 4759/4885GRIK1 4277/4885 |
| US-20070214517-A1 | Sequence-determined DNA fragments and corresponding polypeptides encoded thereby | RNGTT, CPSF1, CPSF6 | ALDH1A1 4769/4885ALOX15 4864/4885GRIK1 4322/4885 |
| US-20120159672-A1 | Sequence-determined DNA fragments and corresponding polypeptides encoded thereby | RNGTT, CPSF1, CPSF6 | ALDH1A1 4769/4885ALOX15 4864/4885GRIK1 4322/4885 |
| US-20100037355-A1 | SEQUENCE-DETERMINED DNA FRAGMENTS AND CORRESPONDING POLYPEPTIDES ENCODED THEREBY | RNGTT, CPSF1, CPSF6 | ALDH1A1 4769/4885ALOX15 4864/4885GRIK1 4322/4885 |
| US-20100021423-A1 | Heterocyclic antiviral compounds | POLR2A, RRM2B, RRP1B | ALDH1A1 1136/4885ALOX15 3752/4885GRIK1 4795/4885 |
| US-20060048240-A1 | Sequence-determined DNA fragments and corresponding polypeptides encoded thereby | RNGTT, CPSF1, CPSF6 | ALDH1A1 4769/4885ALOX15 4864/4885GRIK1 4322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.