Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 4/20 | 0.39 |
| ▸ | CHRNG | P07510 | 4/20 | 0.39 |
| ▸ | CHRNB1 | P11230 | 4/20 | 0.39 |
| ▸ | CHRND | Q07001 | 4/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285888 | 1.00 | CHRNB2 (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4CHRNA1 | |
| SCHEMBL7296888 | 0.87 | BMP1 (0.48) | — | |
| SCHEMBL2354522 | 0.82 | SLC15A2 (0.46) | CHRNA1CHRNGCHRNB1CHRNDCALCRL | |
| SCHEMBL2354514 | 0.82 | SLC15A2 (0.46) | CHRNA1CHRNGCHRNB1CHRNDCALCRL | |
| SCHEMBL2243025 | 0.81 | SLC15A2 (0.45) | CHRNA1CHRNGCHRNB1CHRNDCALCRL | |
| SCHEMBL2814077 | 0.81 | SLC15A2 (0.47) | MMP2CALCRLITGB3ITGA2B | |
| SCHEMBL7286963 | 0.81 | PSMB5 (0.51) | MMP2MMP1MMP3MMP8 | |
| SCHEMBL7286971 | 0.81 | PSMB5 (0.51) | MMP2MMP1MMP3MMP8 | |
| SCHEMBL2193829 | 0.81 | SLC15A2 (0.35) | CHRNB2CHRNB4CHRNA3CHRNA4MMP2 | |
| SCHEMBL7285504 | 0.80 | CTSS (0.50) | MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0264106-B1 | 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use | BANYU PHARMA CO LTD (JP) | 1994-03-16 | — | — | EP | disclosed |
| US-4851387-A | RENIN INHIBITORS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| EP-0264106-A2 | 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use | Banyu Pharmaceutical Co., Ltd. (JP) | 1988-04-20 | — | — | EP | disclosed |